Futuristic airport body scanner emitting gentle terahertz waves.

Terahertz Fields: Are They Really as Safe as We Think?

"New research explores the impact of 0.106 THz electromagnetic fields on genomic damage in vitro, offering insights into the safety of emerging technologies."


Terahertz electromagnetic fields, occupying the frequency range between 0.1 and 10 THz, are beginning to permeate various applications, from advanced body scanners to high-speed data transmission. As our exposure to these fields increases, understanding their potential biological effects becomes paramount. While millimeter waves, which sit just below the terahertz range, are already in use, the push for higher frequencies raises questions about safety.

Despite the growing prevalence of terahertz technology, research into its biological effects remains limited. This gap in knowledge underscores the need for comprehensive studies to assess potential risks and establish safety guidelines. Previous research has primarily focused on radiofrequency electromagnetic fields, with inconsistent findings regarding non-thermal effects at low power intensities.

To address this uncertainty, a recent study investigated the genotoxic potential of 0.106 THz electromagnetic fields on human cells in vitro. The study exposed cells to varying power intensities of 0.106 THz fields and measured genomic damage at the chromosomal level, as well as DNA strand breaks. This research provides valuable insights into the safety profile of terahertz technology and its potential impact on human health.

Unpacking the Study: Terahertz Fields and Genomic Damage

Futuristic airport body scanner emitting gentle terahertz waves.

The study, conducted by Hintzsche et al., meticulously examined the effects of 0.106 THz electromagnetic fields on different human cell types. Cells were exposed to the fields for varying durations (2h, 8h, and 24h) and at different power intensities (0.04 mW/cm² to 2 mW/cm²), representing levels below, at, and above current safety limits. The researchers then assessed genomic damage using two well-established methods: the micronucleus assay and the comet assay.

The micronucleus assay is a widely used technique for detecting chromosomal damage. It identifies micronuclei, which are small, additional nuclei that form when chromosomes or chromosome fragments are not properly incorporated into daughter cells during cell division. The presence of micronuclei indicates that the cell has experienced some form of genomic instability.

  • The comet assay, also known as single-cell gel electrophoresis, is a sensitive method for detecting DNA strand breaks and alkali-labile sites. In this assay, cells are embedded in agarose gel, lysed, and subjected to electrophoresis. Damaged DNA migrates away from the cell nucleus, forming a "tail" that resembles a comet. The length and intensity of the tail are proportional to the amount of DNA damage.
The results of the study were reassuring. The researchers found no evidence of DNA strand breaks or alkali-labile sites in the comet assay, nor did they observe any increase in chromosomal damage in the form of micronucleus induction. These findings suggest that exposure to 0.106 THz electromagnetic fields, under the conditions tested, does not induce manifest genomic damage in vitro.

The Verdict: Proceed with Caution, Not Alarm

While this study provides valuable insights into the safety of 0.106 THz electromagnetic fields, it is essential to interpret the results within the context of the experimental design. The study was conducted in vitro, meaning that the cells were exposed to the fields in a controlled laboratory setting. In vivo studies, which examine the effects of terahertz fields on living organisms, are needed to confirm these findings and to assess potential systemic effects.

Furthermore, the study focused on a specific frequency (0.106 THz) and a limited range of power intensities. Additional research is needed to investigate the effects of other terahertz frequencies and power levels, as well as the potential for cumulative or long-term exposure.

As terahertz technology continues to evolve and find new applications, ongoing research and vigilance are crucial to ensure its safe and responsible deployment. By proactively investigating potential health risks and establishing appropriate safety guidelines, we can harness the benefits of this promising technology while protecting public health.

About this Article -

This article was crafted using a human-AI hybrid and collaborative approach. AI assisted our team with initial drafting, research insights, identifying key questions, and image generation. Our human editors guided topic selection, defined the angle, structured the content, ensured factual accuracy and relevance, refined the tone, and conducted thorough editing to deliver helpful, high-quality information.See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1371/journal.pone.0046397, Alternate LINK

Title: Terahertz Electromagnetic Fields (0.106 Thz) Do Not Induce Manifest Genomic Damage In Vitro

Subject: Multidisciplinary

Journal: PLoS ONE

Publisher: Public Library of Science (PLoS)

Authors: Henning Hintzsche, Christian Jastrow, Thomas Kleine-Ostmann, Uwe Kärst, Thorsten Schrader, Helga Stopper

Published: 2012-09-27

Everything You Need To Know

1

What are Terahertz electromagnetic fields, and where are they being used?

Terahertz electromagnetic fields occupy the frequency range between 0.1 and 10 THz. They're being used in advanced body scanners and for high-speed data transmission. Millimeter waves are already in use and sit just below the terahertz range. As we use higher frequencies, we must ask questions about the safety of terahertz technology. More research is needed to know the biological effects.

2

How was the study conducted to assess the impact of terahertz fields on human cells?

The study examined the genotoxic potential of 0.106 THz electromagnetic fields on human cells in vitro. Hintzsche et al. exposed cells to 0.106 THz fields for varying durations (2h, 8h, and 24h) and at different power intensities (0.04 mW/cm² to 2 mW/cm²). Genomic damage was assessed using the micronucleus assay and the comet assay.

3

Can you explain what the micronucleus assay and the comet assay measure?

The micronucleus assay detects chromosomal damage by identifying micronuclei. These are small nuclei that form when chromosomes or fragments aren't properly incorporated into daughter cells during division. This indicates genomic instability. The comet assay detects DNA strand breaks. Cells are embedded in gel, lysed, and subjected to electrophoresis. Damaged DNA migrates, forming a "comet" tail, which is proportional to the amount of DNA damage.

4

What were the main findings of the study regarding genomic damage?

The study found no evidence of DNA strand breaks or alkali-labile sites in the comet assay. There was no increase in chromosomal damage in the micronucleus induction. This suggests that exposure to 0.106 THz electromagnetic fields, under the tested conditions, does not induce genomic damage in vitro. But it's important to note the results are within the context of the experimental design.

5

What are the implications of this study, and what further research is needed?

The study by Hintzsche et al. provides insights into the safety of 0.106 THz electromagnetic fields. However, because the study was conducted in vitro, the findings might not fully represent what happens in a living organism. In vivo studies are needed to confirm these results and assess potential systemic effects. Future research should explore other frequencies within the terahertz range and consider long-term exposure effects.

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