Surreal illustration of a patient empowered by a personalized medication schedule.

Medication Adherence: Can a Simple Review Make a Big Difference?

"Unpacking how pharmacotherapy reviews can empower hypertensive patients to take control of their health and improve medication adherence."


For adults managing hypertension, consistent medication is essential, and often involves multiple drugs to address the condition, reduce risk factors, and manage complications. However, this complexity can lead to a common challenge: low medication adherence, hindering effective blood pressure control and increasing the risk of complications.

Non-adherence to medication is a widespread issue, with the World Health Organization estimating that approximately 50% of patients forget to take their medications as prescribed. In Brazil, studies reveal that only about a third of hypertensive patients consistently adhere to their medication plans.

Pharmacotherapy review provides a potential solution. It's a structured assessment that fosters a collaborative partnership between patients and healthcare providers, ensuring treatment goals are understood, dosages are agreed upon, and administration schedules are clear. By focusing on improving medication adherence through optimized schedules, can pharmacotherapy reviews improve health outcomes for hypertensive patients?

How a Pharmacotherapy Review Works: A Step-by-Step Approach

Surreal illustration of a patient empowered by a personalized medication schedule.

A research study published in the Brazilian Journal of Pharmaceutical Sciences investigated the impact of pharmacotherapy reviews on medication adherence and blood pressure control among hypertensive patients. The study followed an uncontrolled intervention model, divided into three distinct stages:

The study meticulously collected data on patient profiles, including their existing medications and preliminary adherence assessments. A comprehensive review report was then provided to each patient, containing a detailed assessment of their medication regimen. The study finally evaluated the impact of the review by assessing changes in blood pressure and medication adherence.

  • Stage 1: Initial Assessment: Researchers gathered data on patient demographics, medication history, daily routines, physical activity, diet, and stress levels. They assessed medication adherence using the Morisky-Green test and a self-evaluation scale. Blood pressure was also measured.
  • Stage 2: Review and Intervention: Patients received a personalized pharmacotherapy review report, incorporating their daily routines. The report outlined optimized medication schedules and addressed potential drug-food interactions.
  • Stage 3: Follow-Up Evaluation: After four to six weeks, researchers reassessed medication adherence using the Morisky-Green test, self-evaluation, and blood pressure measurements. They also gathered patient feedback on the review report and its impact on their adherence.
The study involved 40 patients with a mean age of 58.0 years, of whom 72.5% were women. The results demonstrated that 82.5% of patients required some form of intervention following the pharmacotherapy review. This underscores the potential for these reviews to address specific adherence challenges.

Key Findings and the Path Forward

The study revealed significant improvements in medication adherence, as measured by both the Morisky-Green test (p<0.001) and self-reported assessments (p=0.004). Furthermore, there was a notable improvement in blood pressure control, with significant reductions in both systolic (p<0.001) and diastolic (p=0.002) blood pressure levels, and an increased number of patients achieving controlled hypertension (p=0.006).

While the pharmacotherapy review enhanced medication adherence and blood pressure control, it also led to a slight increase in the complexity of treatment regimens. This highlights the importance of ongoing support and education to help patients manage their medication schedules effectively.

Pharmacotherapy reviews hold considerable promise for improving medication adherence and hypertension management. Further research is needed to explore the long-term effects of these interventions and to identify strategies for optimizing their implementation in community pharmacies. By empowering patients with knowledge and support, we can significantly improve health outcomes and reduce the burden of hypertension.

About this Article -

This article was crafted using a human-AI hybrid and collaborative approach. AI assisted our team with initial drafting, research insights, identifying key questions, and image generation. Our human editors guided topic selection, defined the angle, structured the content, ensured factual accuracy and relevance, refined the tone, and conducted thorough editing to deliver helpful, high-quality information.See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1590/s1984-82502015000400002, Alternate LINK

Title: Pharmacotherapy Review: A Proposal To Improve Medication Adherence Among Hypertensive Patients

Subject: General Pharmacology, Toxicology and Pharmaceutics

Journal: Brazilian Journal of Pharmaceutical Sciences

Publisher: FapUNIFESP (SciELO)

Authors: Cláudia Coelho Rigoni, Evelin Soares De Brito, Graziela Modolon Alano, Dayani Galato

Published: 2015-12-01

Everything You Need To Know

1

What exactly is a pharmacotherapy review?

A pharmacotherapy review is a structured assessment of a patient's medication regimen. It involves a collaborative partnership between patients and healthcare providers. This process ensures treatment goals are understood, dosages are agreed upon, and administration schedules are clear. The pharmacotherapy review is designed to enhance medication adherence by optimizing schedules and addressing potential issues, ultimately improving health outcomes for hypertensive patients.

2

Why is medication adherence important for people with hypertension?

Medication adherence refers to the extent to which a patient follows the prescribed instructions for taking their medications. This is crucial, especially for individuals managing hypertension, as consistent medication is essential for controlling blood pressure, reducing risk factors, and managing potential complications. Poor medication adherence can lead to uncontrolled hypertension, increasing the risk of serious health issues. The study highlights that pharmacotherapy reviews significantly improved medication adherence, measured by both the Morisky-Green test and self-reported assessments.

3

What is the Morisky-Green test and how is it used?

The Morisky-Green test is a tool used to assess medication adherence. It is a self-reported questionnaire that helps determine how well a patient is following their medication schedule. The study used the Morisky-Green test, along with self-evaluation scales, to measure medication adherence before and after pharmacotherapy reviews. This allowed researchers to quantify the impact of the reviews on patients' adherence to their prescribed medications.

4

What were the key findings of the study and what do they mean for patients?

The key findings of the study are significant because they demonstrate the effectiveness of pharmacotherapy reviews in improving health outcomes for hypertensive patients. The research showed notable improvements in medication adherence, as measured by both the Morisky-Green test and self-reported assessments. Moreover, there was a significant reduction in both systolic and diastolic blood pressure levels. These improvements highlight the potential of pharmacotherapy reviews as a valuable tool in hypertension management, leading to better blood pressure control and improved patient health.

5

What are the different stages involved in a pharmacotherapy review?

The three stages of the pharmacotherapy review process are: Initial Assessment, Review and Intervention, and Follow-Up Evaluation. In Stage 1, researchers collect data on patient profiles, including medication history, daily routines, and adherence assessments using the Morisky-Green test. Stage 2 involves providing patients with a personalized pharmacotherapy review report, which includes optimized medication schedules and addresses potential drug-food interactions. In Stage 3, researchers reassess medication adherence and blood pressure, and gather patient feedback. These stages provide a comprehensive approach to improve medication adherence and manage hypertension effectively.

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