Liver Cirrhosis and Colonoscopies: What You Need to Know About Bleeding Risks
"A new study sheds light on the increased risk of immediate bleeding after colonoscopies in patients with advanced liver cirrhosis, emphasizing the need for careful evaluation and management."
Colorectal cancer is a significant health concern worldwide, ranking as the third most common cancer and the second leading cause of cancer-related deaths. Colonoscopies have emerged as a vital tool in screening for colorectal neoplasms, allowing for the early detection and removal of potentially cancerous polyps.
Colonoscopic polypectomy, the procedure to remove these polyps, has been proven to reduce both the incidence and mortality of colorectal cancer. While generally safe, colonoscopies are not without risks. Bleeding, perforation, and even death can occur, with post-polypectomy bleeding (PPB) being a relatively common complication.
For individuals with liver cirrhosis, undergoing a colonoscopy adds another layer of complexity. Liver cirrhosis, a chronic condition characterized by scarring of the liver, can disrupt normal blood clotting processes, potentially increasing the risk of bleeding during and after medical procedures. A recent study published in the Yonsei Medical Journal has investigated this specific risk, providing valuable insights for both doctors and patients.
Decoding the Bleeding Risk: What the Study Revealed

The Yonsei Medical Journal study aimed to evaluate the risk of immediate post-polypectomy bleeding (IPPB) in patients with liver cirrhosis undergoing colonoscopic polypectomy. The researchers compared 89 patients with liver cirrhosis to a control group of 348 individuals without liver disease. Key findings highlighted a significantly increased incidence of IPPB in cirrhotic patients with Child-Pugh class B or C (more advanced stages of cirrhosis) compared to those with Child-Pugh class A (less severe cirrhosis) or the control group.
- Advanced Cirrhosis (Child-Pugh Class B or C): Patients with more severe liver cirrhosis had a 3.5 times higher risk of immediate bleeding.
- Large Polyps: Polyps larger than 10mm in size were associated with a 3.6 times increased risk.
- Pedunculated Polyps: These polyps, which have a stalk-like structure, carried a 2.4 times higher risk compared to non-pedunculated polyps.
Making Informed Decisions: What This Means for You
If you have liver cirrhosis and are scheduled for a colonoscopy, it's crucial to have an open and honest conversation with your doctor. Discuss your Child-Pugh score (if known) and any concerns you may have about bleeding risks. Your doctor may recommend additional precautions, such as closer monitoring during the procedure or alternative polyp removal techniques. Remember, proactive communication and a thorough understanding of your individual risk factors are key to ensuring a safe and successful colonoscopy.