Surreal illustration of a heart intertwined with pacemaker leads, symbolizing heart health and technology.

Heart Health SOS: Are Your Pacemaker Leads Putting You at Risk?

"New research sheds light on the long-term performance of pacing leads, revealing potential risks and what you need to know to protect your heart."


For many, pacemakers are a lifeline, providing essential support to regulate heart rhythms and maintain overall well-being. These small devices rely on leads, thin wires that deliver electrical impulses to the heart. While pacemakers have greatly improved in design and function, recent research suggests that certain types of pacing leads may come with unforeseen risks, potentially leading to malfunctions and the need for further intervention.

A new study published in Heart Rhythm, the official journal of the Heart Rhythm Society, delves into the long-term performance of a specific family of pacing leads, revealing important insights that could impact patient care and device selection. Understanding these findings is crucial for anyone with a pacemaker, as well as their families and caregivers.

This article breaks down the key findings of the study, explains the potential risks associated with certain pacing leads, and provides actionable information to help you advocate for your heart health. We'll explore the types of leads involved, the observed malfunction rates, and what this means for the future of pacemaker technology.

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How Common Are Lead Problems?

Lead fracture is reported to occur at a rate ranging from 0.1% to 4.2% per patient-year, with the annual failure rate rising progressively as time passes after implantation. Clinically, these failures can surface in surprising ways: one case report describes left arm twitching that was synchronous with pacing on monitor electrocardiography, traced to insulation failure in the atrial pacing lead. Device-generated noise is another marker of trouble, and a research study set out to measure the incidence of such noise in Tendril and Medtronic 5076 pacemaker leads while assessing whether remote monitoring can help catch malfunction early. Taken together, these figures and cases illustrate that lead issues are an ongoing, quantifiable risk rather than a rare curiosity.

The Limits of Routine Monitoring

The standard path for managing leads is routine surveillance, but the sources show that normal checks do not guarantee a trouble-free lead. In one case, a patient with a dual-lead pacemaker (right atrial and right ventricular) implanted 12 years earlier via the cephalic vein had annual pacemaker checks, all within expected parameters, before developing late-onset lead-associated thrombosis. Lead malposition is another recognized failure mode, and one report notes it can mislead diagnosis, especially when right-bundle-branch-block patterns appear, with transthoracic echocardiography revealing a lead misplaced through a 2-cm interatrial communication. When leads malfunction or the system becomes infected or eroded, transvenous lead extraction is often required, a procedure that may carry greater risk for cardiac resynchronization therapy patients with increased comorbidities. These cases underscore that accepted methods of monitoring and intervention still leave room for late, hard-to-anticipate complications.

Lessons From Years of Implanted Leads

Long-term follow-up of implanted leads has built much of today's understanding of how pacemakers fail. Symptoms of lead fracture vary widely, depending on the patient's pacemaker-dependency and on the degree of loss of capture, and may include lightheadedness, syncope, and extracardiac stimulation. Case experience also links lead misplacement to serious downstream risk: a report describes a patient who had carried a pacemaker for 11 years after implantation for second-degree AV block and later faced potential stroke risk from a lead positioned in the left ventricle. Such accumulated case evidence is foundational, demonstrating that even years after a seemingly well-functioning implant, structural and positional problems can emerge.

The Tendril Lead Study: Unveiling the Risks

Surreal illustration of a heart intertwined with pacemaker leads, symbolizing heart health and technology.

The Heart Rhythm study focused on the long-term performance of the Abbott/St. Jude Tendril pacing lead family, analyzing data from nearly 10,000 leads implanted over a decade at a single center. The research team sought to compare the Tendril leads to other commonly used pacing leads, including Medtronic CapSure Fix Novus and Boston Scientific Fineline II Sterox Pacing EZ Leads. The primary goal was to determine the incidence of lead malfunction, assessed through rigorous Kaplan-Meier analysis, a statistical method used to estimate the probability of an event over time.

The study revealed a concerning trend: Tendril leads exhibited a significantly higher rate of malfunction compared to non-Tendril leads. Over a five-year period, the malfunction rate for Tendril leads was 7.0%, versus only 2.1% for the comparison group. Among the Tendril family, the 1888 TC model showed the highest failure rate at 9.9%, followed by the 1688 and 2088 models at 5.7% and 5.2%, respectively. These findings raise important questions about the design and materials used in Tendril leads.

  • Higher Malfunction Rates: Tendril leads had a significantly higher malfunction rate compared to other leads.
  • Specific Models at Risk: The Tendril 1888 TC model showed the highest failure rate.
  • Long-Term Concerns: Malfunction rates increased over time, particularly after five years.
  • Impact on Patients: Lead malfunctions can lead to additional surgeries and interventions.
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Spotting Malfunction Through Remote Monitoring

Recent research has focused on identifying lead malfunction earlier, with remote monitoring emerging as a key tool. A study of Tendril and Medtronic 5076 pacemaker leads was designed to assess the incidence of lead noise in the investigators' cohort and, in doing so, evaluate how useful remote monitoring is for identifying lead malfunction. The research points toward device-generated noise as an early signal that a lead may be failing. As the authors frame it, the utility of remote monitoring for catching such problems before they become symptomatic is a central question for the field.

Reasons for Caution and Rebuttals

Not all evidence points toward pervasive lead failure, and some caution is warranted in interpreting the available reports. Many implanted leads continue to function normally for years, and single-center studies or individual case reports may overstate how representative a given problem is. It is also possible that public attention to lead alerts can outpace the actual clinical reliability of most devices. That said, acknowledged failures in lead design and manufacturing have, at various times, prompted recalls and re-examination of standard practice. The honest reading is that risk varies by lead model, patient, and time since implantation, making both generalized alarm and blanket reassurance premature.

One Lead Model Under Scrutiny

Comparative data point to meaningful differences between lead models. In a comparative analysis, Tendril leads demonstrated a significantly higher risk of repeated low impedances and noise compared with other manufacturers' models. The authors report concern that these findings may reflect early insulation failure and call for increased scrutiny. This kind of head-to-head evidence matters because it suggests that risk is not distributed evenly across all devices and that model-specific surveillance may be warranted.

One key aspect of the study focused on the role of Optim insulation, a silicone-polyurethane copolymer used in the 1888 and 2088 Tendril models. While Optim was intended to improve abrasion resistance, the study found that leads with Optim insulation actually had higher malfunction rates over the long term. Specifically, after ten years, the malfunction rate for Optim-insulated Tendril leads was 24.5%, compared to 7.1% for the non-Optim insulated 1688 model. This suggests that Optim insulation, while potentially beneficial in some respects, may have unforeseen drawbacks that contribute to lead failure.

Protecting Your Heart: What You Need to Know

The Heart Rhythm study provides valuable insights into the long-term performance of pacemaker leads, highlighting potential risks associated with the Abbott/St. Jude Tendril family, particularly those with Optim insulation. If you have a pacemaker with Tendril leads, it's crucial to discuss these findings with your cardiologist. Regular check-ups, remote monitoring, and open communication with your healthcare team are essential for ensuring the continued safety and effectiveness of your device. While this study sheds light on potential issues, it also underscores the importance of ongoing research and innovation in the field of cardiac pacing, with the ultimate goal of improving patient outcomes and enhancing the reliability of these life-saving devices.

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Weighing Opinion Against Evidence

Public-facing 'expert opinion' commentary on pacemaker leads varies widely in quality and depth, and much of it is delivered through informal video formats rather than peer-reviewed analysis. In one widely shared expert-opinion video segment, the discussion centers on topics unrelated to cardiac device safety, illustrating how such content can have little to do with the technical substance of lead care. This suggests that viewers should treat opinion content cautiously, since what is labeled 'expert' may not be grounded in cardiac device evidence. For patients, that makes it all the more important to anchor decisions in peer-reviewed studies and clinical case reports rather than popular commentary.

The Move Toward Leadless Devices

Lead-related complications are helping to drive interest in alternatives, most notably leadless pacemakers. Industry reporting shows that leading players in the leadless pacemakers market, including Abbott and Medtronic, are actively pursuing growth through mergers and acquisitions, market penetration initiatives, partnerships, and distribution agreements. The commercial attention these companies are directing at leadless technology suggests it is seen as a major frontier in pacing. If leadless systems continue to mature, they may shift the risk profile away from the lead-based complications that dominate current concerns, though such projections remain subject to future development.

A System-Wide Problem, Not Just a Device One

Lead-related harm sits within a larger set of systemic challenges in cardiac device care. One recurring issue is underreporting: lead malposition is described as a rare, underreported complication during pacemaker implantation, including the inadvertent transarterial placement of temporary pacemaker leads in emergency settings. At the same time, studies assessing lead noise in Tendril and Medtronic 5076 leads highlight that remote monitoring may help surface malfunction that would otherwise go undetected between clinic visits. Together, these reports suggest that improving outcomes depends less on any single device fix than on better detection, reporting, and follow-up infrastructure across the health system.

Living With Uncertainty

Behind every reported lead complication is a patient whose daily life is touched by the device. It is reasonable to expect that anxiety about device failure can weigh on patients and their families, especially after headlines about lead recalls and malfunctions circulate. At the same time, many patients live for years with pacemakers that function normally, and most do not experience lead-related problems. Individual experience will vary with the lead model, the patient's own health, and how carefully the device is followed up over time. The human reality is a mix of reassurance and vigilance, with honest communication from clinicians playing a central role.

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1016/j.hrthm.2018.10.024, Alternate LINK

Title: Long-Term Performance Of A Pacing Lead Family: A Single-Center Experience

Subject: Physiology (medical)

Journal: Heart Rhythm

Publisher: Elsevier BV

Authors: Mikhael F. El-Chami, Birju Rao, Anand D. Shah, Carolyn Wood, Michael Sayegh, Patrick Zakka, Krista Ginn, Lauren Pallotta, Bryanna Evans, Michael H. Hoskins, David Delurgio, Michael Lloyd, Jonathan Langberg, Angel R. Leon, Faisal M. Merchant

Published: 2019-04-01

Everything You Need To Know

1

What specific types of pacing leads were examined in the Heart Rhythm study, and how was their performance evaluated?

The research focused on the Abbott/St. Jude Tendril pacing lead family and compared their performance to other pacing leads such as Medtronic CapSure Fix Novus and Boston Scientific Fineline II Sterox Pacing EZ Leads. The primary measure was the incidence of lead malfunction, assessed using Kaplan-Meier analysis over a decade at a single center.

2

According to the Heart Rhythm study, what were the malfunction rates observed in Tendril leads compared to other types of pacing leads?

The Heart Rhythm study indicated that Tendril leads, particularly the 1888 TC model, exhibited higher malfunction rates compared to non-Tendril leads. For example, over five years, Tendril leads had a malfunction rate of 7.0%, while the comparison group experienced only 2.1%. The 1888 TC model specifically showed a failure rate of 9.9%.

3

What is Optim insulation, and what role did it play in the performance of Tendril leads as revealed by the Heart Rhythm study?

Optim insulation is a silicone-polyurethane copolymer used in some Tendril lead models, such as the 1888 and 2088. While intended to enhance abrasion resistance, the Heart Rhythm study found that Tendril leads with Optim insulation had higher malfunction rates over the long term. After ten years, these leads showed a malfunction rate of 24.5%, significantly higher than the 7.1% rate of the non-Optim insulated 1688 model.

4

What steps should patients with pacemakers and Tendril leads take to protect their heart health, based on the findings of the Heart Rhythm study?

If you have a pacemaker with Tendril leads, especially those with Optim insulation, it is important to discuss the Heart Rhythm study findings with your cardiologist. Regular check-ups, remote monitoring, and clear communication with your healthcare team are essential to ensure the continued safety and effectiveness of your device. These steps can help monitor lead performance and detect potential issues early.

5

What are the broader implications of the Heart Rhythm study for the future of pacemaker technology and research in cardiac pacing?

The observed malfunctions in Tendril leads, particularly those with Optim insulation, highlight the importance of ongoing research and innovation in cardiac pacing. Future developments may focus on improving lead design, materials, and insulation to enhance reliability and reduce malfunction rates. Further investigations may explore alternative materials or designs to mitigate the risks associated with specific components like Optim insulation, aiming to improve patient outcomes and the longevity of pacemaker leads.

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