Unlock the Secrets of Cancer: How Real-Time Cell Monitoring is Changing Everything

The CellASIC ONIX microfluidic platform is a system that allows researchers to observe dynamic cellular processes in real-time. It enables the study of cellular behaviors like proliferation, motility, differentiation, and viability circuits. Researchers can manipulate the cell microenvironment by introducing growth factors, inhibitors, and mimetics. They can also simulate conditions such as pulse exposure to drug compounds. This technology allows for the observation of autophagic, apoptotic, or transmigration events without disrupting the culture environment or altering experimental conditions. It provides key parameter values for therapeutic compound profiling.

Real-time cell monitoring is important because cancer cell transformation is a complex and dynamic process that traditional methods often fail to capture. By observing cells in real-time using microfluidic platforms like the CellASIC ONIX, researchers can gain a deeper understanding of cancer cell behavior, drug responses, and potential therapeutic strategies. Understanding the dynamics of cancer cells, including genomic changes, metabolic reprogramming, and interactions with their environment, is crucial for developing effective cancer therapies. The CellASIC ONIX platform offers new opportunities to discover translocation mechanisms not resolvable by end-point assays and quantify the rate of protein translocation.

Microfluidic platforms, such as the CellASIC ONIX, are significant because they provide unprecedented insights into dynamic cell behavior and drug responses. These platforms allow scientists to observe and analyze cellular processes with high precision in real-time. This real-time observation capability allows for a deeper understanding of cancer cell dynamics and how cancer cells respond to various stimuli, including drugs. The platform can simulate conditions, such as pulse exposure to drug compounds, which further enhances the ability to study drug responses.

The CellASIC ONIX platform has several implications. First, it allows for the discovery of translocation mechanisms not resolvable by end-point assays. Second, it enables the simulation of conditions like pulse exposure to drug compounds. Third, it offers the ability to quantify the rate of protein translocation. Fourth, it provides key parameter values for therapeutic compound profiling. These capabilities lead to a deeper understanding of cancer cell behavior, improved drug development, and the potential for more effective cancer treatments.

Researchers can use the CellASIC ONIX microfluidic platform to study various aspects of cancer cell behavior. They can observe proliferation, motility, differentiation, and viability circuits. They can introduce growth factors, inhibitors, and mimetics to study their effects on cancer cells. They can also manipulate the hypoxic environment. Furthermore, the platform allows for the observation of autophagic, apoptotic, or transmigration events without disrupting the culture environment. This real-time observation capability is critical for understanding the dynamic nature of cancer cells and their responses to different treatments.