Woman post IUI treatment with sperm reaching for light.

The Great IUI Debate: To Rest or Not To Rest After Insemination?

"Does lying down after IUI treatment increase your chances of getting pregnant? A new study sheds light on this common question."


Infertility affects many couples, with about 1 in 10 experiencing difficulties conceiving. Intrauterine insemination (IUI) is a common treatment for couples facing unexplained or mild male infertility. The process involves placing sperm directly into a woman's uterus to increase the chances of fertilization.

Following IUI, a common recommendation has been for women to remain lying down for a short period, typically 10-15 minutes. The idea behind this practice is that it might help the sperm reach the egg more effectively. However, the scientific evidence supporting this recommendation has been a subject of debate.

A recent study published in Human Reproduction has challenged the notion that resting after IUI improves pregnancy rates. This research adds to the growing body of evidence suggesting that immediate mobilization—getting up and moving around right away—may be just as effective. Let's delve into the details of this study and what it means for women undergoing IUI.

Challenging the Bed Rest Myth: A Closer Look at the Study

Woman post IUI treatment with sperm reaching for light.

The study, a single-center randomized controlled trial (RCT) conducted in the Netherlands, involved 498 couples diagnosed with unexplained or mild male subfertility. Participants were randomly assigned to either 15 minutes of supine immobilization (lying down) or immediate mobilization after IUI. The primary outcome was the ongoing pregnancy rate per couple.

The results of the study revealed no significant difference in ongoing pregnancy rates between the two groups. In the immobilization group, 32.2% of couples achieved an ongoing pregnancy, compared to 40.0% in the immediate mobilization group. This suggests that resting after IUI does not improve pregnancy rates, and may even be slightly less effective than getting up and moving around.
  • Study Design: Randomized controlled trial.
  • Participants: 498 couples with unexplained or mild male subfertility.
  • Intervention: 15 minutes of supine immobilization versus immediate mobilization after IUI.
  • Primary Outcome: Ongoing pregnancy rate per couple.
The researchers also looked at secondary outcomes, including miscarriage rate, multiple gestation rate, live birth rate, and time to pregnancy. No significant differences were found between the two groups for any of these outcomes. This further supports the conclusion that resting after IUI offers no additional benefit.

The Takeaway: Rethinking the IUI Protocol

This study adds to the growing body of evidence questioning the need for routine bed rest after IUI. While lying down for a short period may seem like a harmless practice, it may not offer any real benefit. For women undergoing IUI, the findings suggest that it's perfectly fine to get up and move around immediately after the procedure. This can save time, reduce anxiety, and make the overall experience more convenient.

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