Illustration of tear exchange beneath a scleral lens.

Scleral Lenses: Are Your Eyes Getting Enough Oxygen?

"A new study explores tear exchange and mixing beneath scleral lenses, revealing insights into lens settling and ocular health."


Scleral lenses are increasingly popular for correcting vision, especially for individuals with irregular corneas or dry eye. Unlike traditional contact lenses, scleral lenses vault over the entire cornea and rest on the sclera (the white part of the eye). This creates a reservoir filled with tears between the lens and the cornea, which provides comfort and constant hydration.

However, this tear reservoir can also trap debris, inflammatory cells, and metabolic by-products. Efficient tear exchange – the process of fresh tears flowing into the reservoir and flushing out old tears – is crucial for maintaining a healthy corneal environment. Without adequate tear exchange, the cornea can be deprived of oxygen and nutrients, potentially leading to discomfort, irritation, and even more serious complications.

New research is shedding light on how tear exchange and mixing occur under scleral lenses. A study by Tse et al. (2018) investigated tear dynamics at different time points during scleral lens wear, providing valuable insights into optimizing lens fitting and promoting ocular health.

AI Search Multiple angles on this topic

Tear Inflow and Exchange

Research on habitual scleral lens wearers has examined tear inflow into the lens system and the turnover of the tear reservoir beneath the lens. One pilot study used fluorophotometry to evaluate tear inflow in wearers with and without midday fogging (MDF). More recent work has investigated how peripheral scleral lens modifications affect tear exchange, including comparisons with a toric landing zone control condition using non-invasive imaging. Another study reapplied sodium fluorescein after 90 minutes of lens settling and analyzed central and peripheral fluorescence with customized MATLAB software.

Current Clinical Approach

Scleral lenses are generally discussed as devices that rest on the sclera while creating a tear-filled space over the cornea. In practice, clinicians must consider lens fit, the tear reservoir, oxygen transmission, and patient comfort together rather than treating any one feature as the sole measure of success. Because outcomes can vary with lens design, wear duration, and individual ocular conditions, broad claims about a single standard approach should be made cautiously.

From Fluidless Designs to Modern Vaults

Scleral lenses are large lenses that rest on the sclera and create a tear-filled vault over the cornea. Historical accounts describe scleral lenses as among the earliest manufactured contact lenses, with designs evolving substantially over time. By the 1930s, some designs had become “fluidless” lenses that used the patient’s own tear film rather than a filling solution and were primarily intended to correct more regular refractive errors. Modern reviews continue to examine how scleral lenses interact with the eyelids and tear film and identify areas requiring further research.

Tear Exchange and Lens Settling: What the Research Reveals

Illustration of tear exchange beneath a scleral lens.

The study used a technique called the "Out-in method," where a small amount of fluorescent dye is placed on the conjunctiva (the clear membrane covering the white part of the eye). Researchers then measure the time it takes for the dye to appear in the tear reservoir under the lens. This indicates how quickly tears are flowing into the space.

In addition to the Out-in method, researchers used a modified slit-lamp technique called fluorography to observe tear dynamics under the lens. This involved taking snapshots of the tear reservoir at regular intervals and measuring the fluorescence intensity, which indicates the concentration of the dye. High-resolution optical coherence tomography (OCT) was also used to measure the thickness of the tear layer.

  • Tear Exchange: 60% of subjects experienced tear flow into the reservoir within 5 minutes after 5 hours of lens wear.
  • Lens Settling: Lens settling, the gradual sinking of the lens onto the eye, also played a role in tear dynamics. About 27% of the change in fluorescence under the lens was due to settling.
  • Tear Mixing: Roughly 13% was due to tear exchange and mixing, while the remaining 60% was a combination of the three factors: tear exchange, mixing and lens settling.
AI Search Multiple angles on this topic

New Directions in Tear Exchange

Recent research has compared scleral lenses with toric landing zones against spherical designs and reported greater central and peripheral tear exchange with the toric design despite comparable lens settling. Another study is examining relationships among tear exchange, the optical density of the fluid reservoir, and patient-reported midday fogging in established scleral lens wearers. A Contact Lens Spectrum report also describes innovative channel modifications intended to enhance tear exchange and mitigate common complications, according to findings by Dr. Melissa Barnett.

Remaining Uncertainties

Scleral lenses can offer important optical and surface benefits, but they are not free of potential limitations. Tear exchange, lens settling, fluid-reservoir characteristics, and individual fit may influence performance and comfort. The available material does not establish that one design or modification consistently prevents every complication, so expectations should remain individualized and evidence-based.

Oxygen Transmission Tradeoffs

Modern scleral lenses are fabricated from high oxygen-permeable materials, but their relatively thick profiles and limited tear exchange may modestly reduce oxygen transmission to the central cornea. The cited comparative evaluation indicates that this concern may be particularly relevant during continuous wear. Thus, material oxygen permeability is only one part of the comparison; lens thickness, tear exchange, and wearing schedule also matter.

The study also found that lens settling can affect tear exchange. As the lens settles, the tear reservoir thins, which can reduce the flow of fresh tears into the space. This highlights the importance of proper lens fitting to minimize settling and ensure adequate tear exchange. Some participants in the study experienced no tear flow after 5 hours of wear, with fluorescence decline due to lens settling.

What This Means for Scleral Lens Wearers

The research suggests that tear exchange continues to occur under scleral lenses, even after several hours of wear. However, lens settling can impact tear dynamics, potentially reducing the flow of fresh tears to the cornea.

AI Search Multiple angles on this topic

Designing for Better Exchange

The emerging discussion around scleral lenses increasingly emphasizes tear exchange alongside oxygen-permeable materials and optical performance. A Contact Lens Spectrum report highlights innovative channel modifications as a way to enhance tear exchange and mitigate common complications. The report attributes these recent findings to Dr. Melissa Barnett, suggesting that design changes may become an important focus of scleral lens refinement.

Expanding Designs and Applications

A 2026 overview describes scleral lenses as providing comfort and clarity for people with conditions such as keratoconus or severe dry eye. It also emphasizes the tear-filled reservoir as a feature that helps maintain eye moisture and reduce discomfort. A separate 2026–2031 market report identifies mini and large scleral lens designs, dry eye and keratoconus as key drivers, regional trends, and major players as areas of industry analysis.

Balancing Benefits and Constraints

Scleral lens care sits at the intersection of vision correction, ocular-surface management, fit quality, and ongoing monitoring. Benefits may be substantial for some users, but outcomes can depend on individual anatomy, lens design, wearing habits, and access to appropriate clinical follow-up. These factors make generalized promises difficult and support a cautious, personalized approach.

Patient Experience Matters

For patients, the practical value of a scleral lens is measured not only by visual performance but also by comfort, moisture, and the ability to manage daily wear. Experiences may differ because ocular conditions and responses to lens fit are individual. Clinicians and patients therefore need to weigh reported benefits against tolerance, handling demands, and any symptoms that arise during wear.

To promote optimal ocular health, it's crucial to have scleral lenses properly fitted by an eye care professional. A well-fitted lens will minimize settling and maintain an adequate tear reservoir, ensuring sufficient tear exchange.

If you wear scleral lenses and experience discomfort, dryness, or blurry vision, consult with your eye care provider. They can assess your lens fit, evaluate your tear dynamics, and recommend strategies to improve ocular surface health.

Different measures describe different parts of tear movement

Descriptions of tear exchange use either dye placed on the conjunctiva to track its entry into the reservoir, or dye placed inside the lens bowl to track dilution or exit. These approaches follow movement in opposite directions, rather than defining tear exchange and mixing as interchangeable for scleral lenses.[1] [2]

A comparison reported tear exchange within five minutes in 64% of eyes, while another cited report described only 10% of participants as having a high flow rate after five hours and 40% as having a low rate. These figures describe different categories and observation contexts, so they are not direct estimates of the same outcome.[1] [3]

Fluorescence decline beneath a scleral lens cannot be assigned directly to exchange or mixing because thinning of the post-lens tear film and reduced dye concentration both contribute. The relative roles of lens settling and tear exchange in that decline remain unclear, limiting what fluorescence alone can say about fluid movement.[2]

The cited literature also includes examination of tear dynamics in modern high-Dk, non-fenestrated scleral lenses, but that citation context does not establish when those investigations occurred or provide their results.[1]

What remains unresolved about scleral lens tear dynamics

  • How much of fluorescence decline reflects tear-film thinning versus dye dilution, and how much reflects settling versus exchange? The available descriptions identify both combined effects and unresolved relative contributions.[2]
  • Do entry-based and dilution-or-exit-based measurements capture the same aspects of exchange, or distinct parts of tear movement? The methods track different dye paths, while scleral lens exchange and mixing are not treated as synonymous.[1] [2]

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1016/j.clae.2018.11.016, Alternate LINK

Title: Tear Dynamics Under Scleral Lenses

Subject: Optometry

Journal: Contact Lens and Anterior Eye

Publisher: Elsevier BV

Authors: Vivien Tse, Bo Tan, Young Hyun Kim, Yixiu Zhou, Meng C. Lin

Published: 2019-02-01

Everything You Need To Know

1

Why are scleral lenses different from regular contacts, and what is the significance of the tear reservoir they create?

Scleral lenses are unique because they vault over the cornea and rest on the sclera, creating a tear reservoir. This reservoir provides constant hydration, beneficial for individuals with dry eye or irregular corneas. However, it can also trap debris and metabolic by-products, which is why tear exchange is so vital. Without sufficient tear exchange, the cornea may not receive enough oxygen and nutrients, leading to discomfort or more serious issues.

2

What research methods like the 'Out-in method', fluorography, and optical coherence tomography (OCT) were used to study tear dynamics under scleral lenses?

The 'Out-in method' involves placing a fluorescent dye on the conjunctiva to measure how quickly tears flow into the reservoir under a scleral lens. Fluorography, a modified slit-lamp technique, takes snapshots of the tear reservoir to measure dye concentration. High-resolution optical coherence tomography (OCT) measures the thickness of the tear layer. These methods help researchers understand tear dynamics and optimize scleral lens fitting.

3

How does the settling of a scleral lens affect tear exchange and what implications does this have for lens fitting?

The research indicates that lens settling, the gradual sinking of the scleral lens onto the eye, can significantly affect tear dynamics. As the lens settles, the tear reservoir thins, potentially reducing the flow of fresh tears. Proper lens fitting is crucial to minimize settling and maintain adequate tear exchange. The study showed that in some participants, fluorescence decline was due to lens settling, with no tear flow after 5 hours of wear.

4

Why is proper tear exchange so important when wearing scleral lenses, and how does this relate to corneal health?

Tear exchange is crucial because it allows fresh tears to flow into the reservoir under a scleral lens, flushing out debris, inflammatory cells, and metabolic by-products. Without adequate tear exchange, the cornea may be deprived of necessary oxygen and nutrients. The study by Tse et al. (2018) revealed that tear exchange continues even after several hours of lens wear, but lens settling can impact tear dynamics.

5

What are the different factors that contribute to tear dynamics under scleral lenses, and what are the implications for lens design and wear?

The study indicates that tear exchange, mixing, and lens settling all play a role in tear dynamics under scleral lenses. Approximately 13% of the fluorescence change was attributed to tear exchange and mixing, while about 27% was due to lens settling. The remaining 60% was a combination of all three factors. These findings emphasize the importance of considering all these dynamics when fitting scleral lenses to promote ocular health. Further research could explore how different lens designs and materials impact these dynamics.

Newsletter Subscribe

Subscribe to get the latest articles and insights directly in your inbox.