Illustration of an eye affected by corneal blood staining after cataract surgery.

Red Alert: How to Avoid Corneal Blood Staining After Cataract Surgery

Theo Raines in Health & Wellness December 2025 • 4 min read.

"A rare complication can cloud your vision. Learn the risk factors and preventative measures for corneal blood staining after cataract surgery."

Cataract surgery is a common and generally safe procedure to restore clear vision. However, like any surgery, it carries potential risks. One rare but serious complication is corneal blood staining, which occurs when blood from a hyphema (bleeding in the anterior chamber of the eye) penetrates the cornea, the clear front part of the eye.

Corneal blood staining can significantly impair vision, causing blurring and, in severe cases, permanent opacity. While it often resolves spontaneously, it can take months or even years, and some individuals may require corneal transplantation to restore sight. Understanding the risk factors and preventative measures is crucial for both patients and surgeons.

This article will explore a recent case study of corneal blood staining following complicated cataract surgery, shedding light on the importance of early intervention and proactive management to minimize the risk of this potentially vision-threatening complication.

Understanding the Case: When Cataract Surgery Leads to Corneal Staining

Illustration of an eye affected by corneal blood staining after cataract surgery.

A 68-year-old woman undergoing routine cataract surgery developed a hyphema due to a posterior capsule rupture and bleeding during anterior vitrectomy. Despite the fact that IOP (intraocular pressure) remained relatively normal after a few days, corneal blood staining was observed.

Several factors contributed to this unfortunate outcome:

Coumadin Use: The patient was taking warfarin (Coumadin), a blood thinner, due to atrial fibrillation. This increased her risk of bleeding during and after surgery.
Surgical Complications: The posterior capsule rupture and subsequent anterior vitrectomy introduced a higher risk of bleeding into the anterior chamber.
IOL Dislocation and Washout: The intraocular lens (IOL) dislocated, requiring repositioning and anterior chamber washout. This additional manipulation may have further irritated the eye and contributed to the hyphema.

The patient was treated with various medications to control inflammation and IOP, but the corneal staining persisted. Warfarin was stopped, and a second anterior chamber washout was performed. Over time, the cornea gradually cleared, and the patient's vision improved, but full resolution took 2.5 years.

Protecting Your Vision: Key Takeaways and Preventative Strategies

This case highlights that even with modern surgical techniques, complications like corneal blood staining can occur after cataract surgery. While a therapeutic INR value of 3 is usually what specialists target while using Coumadin, even these values could lead to hyphema after surgery. It emphasizes the importance of careful patient selection, meticulous surgical technique, and prompt management of any post-operative bleeding.

So, what can patients and surgeons do to minimize the risk?

<ul><li>Careful Pre-operative Assessment: Thoroughly evaluate patients' medical history, including medication use (especially blood thinners) and bleeding disorders. Manage anticoagulation therapy appropriately in consultation with the patient's physician.</li><li>Meticulous Surgical Technique: Employ techniques to minimize the risk of posterior capsule rupture and bleeding.</li><li>Prompt Management of Hyphema: Closely monitor patients for signs of hyphema after surgery. Consider early anterior chamber washout in cases of significant bleeding to prevent corneal staining.</li><li>Consider Early AC Washout: Early surgical intervention for AC washout be considered in order to avoid corneal blood staining.</li></ul>

About this Article -

This article was crafted using a human-AI hybrid and collaborative approach. AI assisted our team with initial drafting, research insights, identifying key questions, and image generation. Our human editors guided topic selection, defined the angle, structured the content, ensured factual accuracy and relevance, refined the tone, and conducted thorough editing to deliver helpful, high-quality information.See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1159/000492612, Alternate LINK

Title: Corneal Blood Staining After Complicated Cataract Surgery

Subject: Ophthalmology

Journal: Case Reports in Ophthalmology

Publisher: S. Karger AG

Authors: Mark Krauthammer, Jorje Mandelblum, Oriel Spierer

Published: 2018-09-07

Everything You Need To Know

What is corneal blood staining?

Corneal blood staining is a serious complication that can occur after cataract surgery. It happens when blood from a hyphema, or bleeding in the anterior chamber of the eye, enters the cornea, which is the clear front part of the eye. This can lead to blurred vision and, in severe cases, permanent vision loss, such as corneal opacity.

What are the main risk factors for corneal blood staining?

Several factors increase the risk of corneal blood staining. The use of blood thinners like Coumadin, as seen in the case, is a significant risk factor because it increases the likelihood of bleeding. Surgical complications, such as posterior capsule rupture and the need for anterior vitrectomy, also elevate the risk. Furthermore, additional procedures like IOL dislocation and anterior chamber washout may irritate the eye and contribute to the hyphema.

Why is early intervention important when dealing with corneal blood staining?

The significance of early intervention and proactive management lies in minimizing the duration of impaired vision and preventing permanent damage. Prompt treatment, including medication to control inflammation and IOP, and procedures like anterior chamber washout, can help manage the condition. Early intervention can increase the chances of the cornea clearing up more quickly and reduce the need for more invasive treatments like corneal transplantation.

What preventative measures can be taken to reduce the risk of corneal blood staining?

Preventative measures are crucial to avoid corneal blood staining. Careful patient selection is the first step, which involves evaluating the patient's overall health, including any medications they are taking, such as Coumadin. Meticulous surgical technique is also essential to minimize the risk of complications. Furthermore, prompt management of any post-operative bleeding, including the administration of medication to control inflammation and IOP, is critical to preventing the progression of corneal blood staining.

What happened in the case study involving corneal blood staining?

The 68-year-old woman's case illustrates the potential for corneal blood staining following cataract surgery. Despite relatively normal IOP, corneal blood staining occurred due to several factors, including Coumadin use, surgical complications like posterior capsule rupture, anterior vitrectomy, and IOL dislocation. The patient's treatment involved various medications and a second anterior chamber washout. The cornea cleared over 2.5 years, highlighting the long-term impact of the condition.