What are infraorbital hollows, and why are they a concern?

Infraorbital hollows, often referred to as tear troughs, are depressions under the eyes that can create a fatigued or aged appearance. These hollows result from volume loss in the under-eye area, a consequence of aging and reduced hyaluronic acid production. Addressing these hollows with treatments like hyaluronic acid fillers aims to restore volume and rejuvenate the area, leading to a more refreshed look.

Why are hyaluronic acid fillers used for infraorbital hollows so important?

Hyaluronic acid fillers are crucial because they replenish the lost volume in the infraorbital area. As individuals age, the body's natural production of hyaluronic acid decreases, which contributes to the formation of hollows. These fillers are designed to restore this volume, creating a smoother, more youthful appearance. The study specifically mentions Juvéderm Voluma, a filler with low hydrophilicity and a long duration of effect, making it a particularly effective option for this purpose.

What are the benefits of using Juvéderm Voluma for treating infraorbital hollows?

The use of Juvéderm Voluma offers several benefits. Its low hydrophilicity minimizes the risk of swelling and overcorrection, which are potential complications with other fillers. Furthermore, the long duration of the filler means that the results can last, reducing the need for frequent touch-ups. Finally, the supraperiosteal placement ensures a more natural-looking result by restoring volume in the deeper layers of the skin, mimicking the natural structure of the under-eye area.

Why is supraperiosteal placement important when using hyaluronic acid fillers?

Supraperiosteal placement is significant because it ensures a natural and sustained outcome. It involves placing the hyaluronic acid filler above the periosteum, which is the membrane covering the bone. This technique allows for restoring volume in the deeper layers of the skin, which is essential for achieving a natural-looking result. This approach is different from traditional methods and contributes to the innovative nature of the study's findings.

Why is the study by Dr. Hall and colleagues significant in the context of cosmetic treatments?

The study by Dr. Hall and colleagues is important because it challenges traditional cautious approaches and opens new possibilities in treating infraorbital hollows. The study highlights the safe and effective use of volumizing hyaluronic acid fillers. It's a novel approach, showing that, when administered by experienced practitioners, these fillers can provide lasting and natural-looking results, leading to improved aesthetic outcomes. This paves the way for more innovative techniques in cosmetic treatments.

Rejuvenated under-eye area after hyaluronic acid filler treatment.

Infraorbital Hollows: The Latest in Hyaluronic Acid Filler Treatments

Jordan Keane in Health & Wellness December 2025 • 4 min read.

"A novel approach using volumizing fillers demonstrates promising results in treating under-eye hollows."

Infraorbital hollows, commonly known as tear troughs, can create a tired or aged appearance. While various treatments exist, the use of hyaluronic acid fillers has gained traction for its ability to restore volume and rejuvenate the under-eye area. A recent study highlights a promising approach using volumizing hyaluronic acid fillers, offering new hope for individuals seeking a refreshed look.

Traditionally, physicians have been cautious about using high viscous modulus (G') fillers in the tear trough area due to concerns about potential complications. However, a study published in JAMA Facial Plastic Surgery commends Dr. Hall and colleagues for their innovative contribution, demonstrating the safe and effective use of volumizing hyaluronic acid fillers in treating infraorbital hollows.

This article will delve into the details of this novel approach, exploring the benefits, considerations, and potential impact on the field of cosmetic treatments. It aims to provide readers with a comprehensive understanding of how hyaluronic acid fillers can be used to address infraorbital hollows effectively.

The Science Behind Volumizing Fillers for Tear Troughs

Rejuvenated under-eye area after hyaluronic acid filler treatment.

Hyaluronic acid is a naturally occurring substance in the body that helps maintain skin hydration and volume. As we age, the production of hyaluronic acid decreases, leading to volume loss and the formation of wrinkles and hollows. Hyaluronic acid fillers are designed to replenish this lost volume, providing a more youthful and refreshed appearance.

The study highlights the use of Juvéderm Voluma, a hyaluronic acid filler known for its low hydrophilicity and long duration. Unlike traditional fillers, Voluma is designed to be placed supraperiosteally, meaning above the periosteum (the membrane covering the bone). This placement allows for a more natural and sustained outcome.

Low Hydrophilicity: Minimizes the risk of swelling and overcorrection.
Long Duration: Provides lasting results, reducing the need for frequent touch-ups.
Supraperiosteal Placement: Ensures a natural-looking result by restoring volume in the deeper layers of the skin.

The study's findings suggest that volumizing hyaluronic acid fillers can be a safe and effective option for treating infraorbital hollows when administered by experienced practitioners. However, it's important to consider individual patient anatomy and choose the appropriate filler based on their specific needs.

The Future of Under-Eye Rejuvenation

The study by Hall et al. opens new possibilities in the treatment of infraorbital hollows. By demonstrating the safe and effective use of volumizing hyaluronic acid fillers, they have challenged traditional approaches and paved the way for more innovative techniques.

While the results are promising, it's essential to acknowledge the limitations of the study. The FACE-Q metric, used to assess patient satisfaction, may not fully capture the nuances of aesthetic outcomes. Further research is needed to explore the long-term effects and optimal use of volumizing fillers in the tear trough area.

Overall, this study marks a significant step forward in the field of cosmetic treatments, offering a potential solution for individuals seeking to rejuvenate their under-eye area. As with any cosmetic procedure, it's crucial to consult with a qualified and experienced practitioner to determine the best course of treatment.