Illustration of a person sleeping with a CPAP mask, with a scale in the background, symbolizing the connection between CPAP therapy and weight.

CPAP and Weight Gain: Unpacking the Connection and What You Can Do About It

Beau Callahan in Health & Wellness November 2025 • 4 min read.

"Is your sleep apnea treatment leading to unwanted pounds? A deep dive into the latest research, offering practical strategies to manage weight while staying compliant with CPAP therapy."

If you've recently been prescribed continuous positive airway pressure (CPAP) therapy for sleep apnea, you're likely experiencing improved sleep quality and daytime energy. However, you might also notice an unexpected side effect: weight gain. This is a common concern among CPAP users, and emerging research is shedding light on the complex relationship between CPAP and changes in body weight.

Obstructive sleep apnea (OSA), characterized by repeated pauses in breathing during sleep, is closely linked to obesity. While weight loss is often recommended as a management strategy for OSA, some studies suggest that CPAP treatment itself can contribute to weight gain. This creates a frustrating paradox for many individuals striving to improve their health.

This article delves into a recent meta-analysis of clinical trials investigating the effects of CPAP on weight and metabolic function. We'll break down the findings, explore potential explanations for this phenomenon, and provide actionable strategies to help you manage your weight while continuing your CPAP therapy.

The CPAP-Weight Gain Connection: Decoding the Research

Illustration of a person sleeping with a CPAP mask, with a scale in the background, symbolizing the connection between CPAP therapy and weight.

A meta-analysis, featured in the Journal of Sleep Research, combined data from multiple randomized, placebo-controlled trials to examine the impact of CPAP therapy on weight and metabolic health. The study analyzed data from 128 patients who underwent CPAP treatment for 2–3 months.

The results indicated a statistically significant, though modest, increase in weight among those using therapeutic CPAP compared to those using a placebo device. Specifically, the average weight gain was 1.17 kg (approximately 2.6 pounds). Interestingly, the study also found a dose-dependent effect: individuals who used CPAP more consistently (more than 4 hours per night) experienced greater weight gain.

Overall Weight Gain: Therapeutic CPAP was associated with a small but significant increase in weight (1.17 kg).
Dose-Dependent Effect: Higher CPAP usage correlated with greater weight gain.
No Metabolic Changes: The study found no significant adverse changes in metabolic markers such as glucose, insulin, cholesterol, or visceral abdominal fat.

It's important to note that while the study revealed a correlation between CPAP use and weight gain, it did not establish a direct cause-and-effect relationship. The weight gain was also relatively small, and the study found no evidence of adverse metabolic consequences.

Key Takeaways

While CPAP therapy can lead to modest weight gain in some individuals, the benefits of treating sleep apnea—improved sleep quality, reduced daytime sleepiness, and decreased risk of cardiovascular problems—generally outweigh this side effect. If you're concerned about weight gain while using CPAP, talk to your doctor about strategies to manage your weight, such as diet and exercise.

About this Article -

This article was crafted using a human-AI hybrid and collaborative approach. AI assisted our team with initial drafting, research insights, identifying key questions, and image generation. Our human editors guided topic selection, defined the angle, structured the content, ensured factual accuracy and relevance, refined the tone, and conducted thorough editing to deliver helpful, high-quality information.See our About page for more information.

Everything You Need To Know

Can using CPAP therapy actually lead to weight gain, and if so, how significant is it?

Yes, research indicates that continuous positive airway pressure (CPAP) therapy can lead to a modest weight gain in some individuals. A meta-analysis found an average weight increase of about 1.17 kg (approximately 2.6 pounds) among those using therapeutic CPAP. While this weight gain is statistically significant, it's considered relatively small. The study didn't find any adverse metabolic consequences, but it's important to consider the overall health context. It is also important to note this study didn't establish a direct cause-and-effect relationship; it showed correlation.

Does the amount of time I use my CPAP machine each night affect my chances of gaining weight?

Yes, the study indicated a dose-dependent effect, revealing that individuals who used continuous positive airway pressure (CPAP) more consistently, specifically for more than 4 hours per night, experienced greater weight gain. This suggests a correlation between the duration of CPAP use and the extent of weight gain. The precise mechanisms behind this correlation are still being investigated, and further research is needed to fully understand the relationship.

I've heard that sleep apnea is linked to obesity. If I'm using CPAP to treat my sleep apnea, why might I still gain weight?

Obstructive sleep apnea (OSA) is often associated with obesity, and weight loss is frequently recommended as a management strategy. However, continuous positive airway pressure (CPAP) therapy can sometimes contribute to weight gain, creating a frustrating paradox. The reasons for this aren't fully understood, but potential factors include changes in metabolism, hormonal regulation, and increased appetite due to improved sleep quality. While the study showed no significant adverse changes in metabolic markers, the interplay between OSA, CPAP, and weight management is complex and requires a holistic approach.

The research mentions that CPAP therapy didn't cause 'adverse metabolic changes.' What does that mean for my overall health?

The study indicated no significant adverse changes in metabolic markers like glucose, insulin, cholesterol, or visceral abdominal fat. This suggests that while continuous positive airway pressure (CPAP) may contribute to modest weight gain, it doesn't appear to negatively impact key metabolic functions. However, maintaining a healthy weight is crucial for overall well-being, particularly for those with obstructive sleep apnea (OSA). It is important to note that the absence of observed changes does not automatically exclude potential for adverse effects in other metabolic dimensions.

If I'm using CPAP and concerned about weight gain, what steps can I take to manage my weight effectively without stopping my therapy?

If you're concerned about weight gain while using continuous positive airway pressure (CPAP), it's crucial to consult your doctor. They can assess your individual situation and recommend appropriate strategies to manage your weight, such as dietary adjustments, regular exercise, and monitoring your metabolic health. It is important to maintain adherence to continuous positive airway pressure (CPAP) therapy, as the benefits of treating sleep apnea—improved sleep quality, reduced daytime sleepiness, and decreased risk of cardiovascular problems—generally outweigh the potential for modest weight gain.