Healthy pig in a green field, symbolizing natural approaches to livestock farming.

Beyond Antibiotics: How Natural Feed Additives & Outdoor Access Can Boost Pig Health

"Discover the potential of mannan oligosaccharides (Bio-Mos) and outdoor housing to improve pig growth and well-being, offering a promising alternative to traditional antibiotic use in livestock farming."


In an era where concerns about antibiotic resistance are escalating, the livestock industry is under increasing pressure to find alternative strategies for promoting animal health and growth. Traditional reliance on antibiotics as growth promoters is being questioned, leading researchers and farmers to explore innovative solutions that prioritize both animal welfare and sustainable practices. This article delves into a compelling study that investigates the potential of mannan oligosaccharides (Bio-Mos) and outdoor access housing systems to enhance pig health, growth, and overall carcass composition.

The study, conducted by researchers at The Ohio State University, examines the effectiveness of Bio-Mos, a prebiotic, in comparison to subtherapeutic antibiotic treatments and conventional housing systems. The core objective is to identify viable alternatives to antibiotics that not only maintain but also improve pig performance and health. This research is particularly relevant as legislative bans on antibiotic use in livestock gain traction globally, pushing the industry towards more sustainable and health-conscious farming methods.

This comprehensive analysis not only sheds light on the immediate benefits of these alternative approaches but also addresses broader implications for the future of swine farming. By understanding the interplay between natural feed additives, housing conditions, and pig physiology, we can pave the way for more responsible and effective strategies in livestock management.

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Responsible Antibiotic Use and Its Limits

Antibiotics may be needed to treat illness in pigs, and the Pork Checkoff describes responsible use as giving only what is necessary for animal health, food safety, and the environment. However, restrictive, barren housing and painful or stressful management practices can predispose high-performance pigs in intensive systems to disease, making antibiotics part of the infrastructure that sustains health and production. Research on alternatives notes that combinations of biologics and immunomodulatory agents may help address these limitations, but the effects of antimicrobial growth promoters and their alternatives on intestinal microbiota, intestinal health, and growth remain diverse and inconsistent.

Unpacking the Science: Bio-Mos and Outdoor Housing

Healthy pig in a green field, symbolizing natural approaches to livestock farming.

The research design was structured as a 3 × 2 factorial experiment, involving 360 pigs from a Landrace breeding female population. The pigs were divided into groups receiving one of three dietary treatments: a control diet, a diet supplemented with Bio-Mos, or a diet including a subtherapeutic antibiotic (tetracycline). The Bio-Mos was administered at varying inclusion rates across different growth phases, ensuring a targeted approach to nutritional support.

In addition to dietary variations, the study also assessed the impact of different housing systems. Pigs were housed in either a conventional indoor facility or an outdoor access system. The conventional indoor (IN) facility provided 1.0 m²/pig of solid concrete space and 0.3 m²/pig of slatted floor, accommodating 12 pigs per pen. The outdoor access (OUT) system offered 1.1 m²/pig of indoor, bedded concrete space and 1.9 m²/pig of outdoor solid concrete, with only 6 pigs per pen. This design acknowledges the potential confounding of space with the number of pigs per pen, allowing for a comprehensive analysis of environmental factors.

  • Bio-Mos (BM): A prebiotic that supports gut health.
  • Antibiotic (AB): Tetracycline, included at 0.0055% in all dietary phases.
  • Control (CON): A standard diet without additives.
  • Indoor (IN): Conventional, indoor facility with limited space per pig.
  • Outdoor Access (OUT): More space per pig with bedded concrete and outdoor area.
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Emerging Feed-Additive Evidence

A study of weaned pigs found that combinations of starch, non-starch polysaccharides, and mannan-oligosaccharide affected gain-to-feed ratio, diarrhea incidence, nutrient digestibility, microbial communities, and short-chain fatty acid concentrations. In a separate intestinal-cell model, adding 150 ppm of a proprietary blend of yeast cell wall, short-chain fatty acids, and zinc proteinate produced greater cell densities than the control and 150 ppm butyrate at 24 hours, alongside greater protein and glucose utilisation. Other research has examined how immune stimulation by porcine reproductive and respiratory syndrome virus alters plasma amino acid flux and dietary nitrogen utilization in starter pigs, while a 2025 Dutch study investigated diseases associated with therapeutic antimicrobial use in weaners and sows with suckling piglets.

Why Antibiotic Reduction Is Difficult

Reducing antibiotic use cannot be separated from the housing and management conditions that influence pig health. Reviews report that restrictive, barren housing and practices causing pain and stress predispose high-performance pigs in intensive systems to disease, with antibiotics then functioning as part of the infrastructure supporting health and high production. Public-health and social research on antimicrobial resistance has also focused heavily on antibiotic use as a practice, underscoring that the debate extends beyond farm productivity.

Limits of the Available Comparison

The listed comparative study concerns 240 day-old commercial broilers, not pigs. It compared floor and cage rearing across three housing zones in an environmentally controlled house during winter. Because the study population and species differ from the subject of this article, its details do not establish a direct comparison of pig housing systems or outdoor access.

Throughout the study, researchers meticulously measured several key indicators, including average daily gain (ADG), average daily feed intake (ADFI), feed conversion ratio (G:F), ultrasonic carcass composition, blood hematocrit levels, and the occurrence of observed illnesses. These measurements provided a detailed view of how each treatment affected pig health and performance. The data collected were then subjected to rigorous statistical analysis to determine the significance of each variable.

Moving Forward: Towards Sustainable Swine Farming

The insights gained from this study offer a promising outlook for the future of swine farming. By integrating natural feed additives like Bio-Mos and optimizing housing conditions to include outdoor access, the industry can move towards more sustainable and responsible practices. These changes can not only reduce our reliance on antibiotics but also promote better animal welfare and improve overall production efficiency. As consumer awareness and regulatory pressures continue to grow, adopting these innovative approaches will be crucial for ensuring the long-term viability and ethical integrity of the swine farming industry.

Growth gains came with a feed-efficiency trade-off

  • 0.1Compared with indoor housing, outdoor-access pigs ate 0.1 kg/d more and gained 0.04 kg/d more, reaching the same weight endpoint 4.0 days sooner; however, gain per kilogram of feed was 0.01 kg lower.[1]
  • 0.02Compared with the antibiotic diet, pigs on Bio-Mos and control diets gained 0.02 kg/d more and reached the endpoint 3 days sooner.[1]

The results separate housing effects from the Bio-Mos comparison

Outdoor access was associated with faster growth, but not better feed conversion: the pigs needed more feed and converted it less efficiently. The housing comparison bundled outdoor access with differences in space and pen size, so it cannot isolate which feature accounts for the pattern.[1]

Bio-Mos did not outperform the no-additive diet on growth in this trial. Both diets did better than the antibiotic diet on the reported growth measures, while the authors noted that Bio-Mos did not increase growth performance over control.[1]

The measured carcass composition did not differ across the dietary or housing groups, so the growth differences did not translate into a detected carcass-composition difference in this study.[1]

What this housing and feeding comparison cannot resolve

  • The authors say the antibiotic diet did not improve growth, efficiency, or health, while Bio-Mos did not increase growth over the control diet.[1]

A factorial trial in grower-finisher pigs

PopulationProgeny of successive farrowings of a Landrace breeding female population[1]
Sample size360[1]
SettingConventional indoor and outdoor access housing systems[1]
ComparisonBio-Mos, tetracycline antibiotic, and no-additive control diets; indoor versus outdoor access housing[1]
Main outcomeDaily growth rate, feed intake, feed conversion, carcass composition, hematocrit, and observed illnesses[1]
Effect sizeOutdoor access increased ADFI by 0.1 kg/d and ADG by 0.04 kg/d, reduced days to endpoint by 4.0 d, and reduced G:F by 0.01 kg gain/kg feed; BM and control diets had 0.02 kg/d greater ADG and reached endpoint 3 days sooner than antibiotic diet[1]
Times cited16[1]

What remains unclear about growth, health, and housing

  • Which component of the outdoor-access system—access itself, space allocation, or pigs per pen—best explains the growth and hematocrit differences?[1]

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.2527/jas.2013-6582, Alternate LINK

Title: Effect Of Mannan Oligosaccharides (Bio-Mos) And Outdoor Access Housing On Pig Growth, Feed Efficiency And Carcass Composition

Subject: Genetics

Journal: Journal of Animal Science

Publisher: Oxford University Press (OUP)

Authors: B. A. Wenner, H. N. Zerby, D. D. Boler, W. A. Gebreyes, S. J. Moeller

Published: 2013-08-13

Everything You Need To Know

1

What is Bio-Mos and what role does it play in the context of the study?

Bio-Mos is a prebiotic that supports gut health in pigs, it was compared to subtherapeutic tetracycline antibiotics and a standard diet in a study. This helps to see the effectiveness of this additive compared to the use of antibiotics. The use of tetracycline is an example of traditional antibiotic use. The study wanted to find alternatives to antibiotics to improve pig performance, health, and overall carcass composition. The study found the Bio-Mos could be used instead of antibiotics.

2

What treatments and systems were compared in the study?

The research compares the use of Bio-Mos, a prebiotic, against traditional antibiotic treatments, specifically tetracycline, and also examines conventional indoor housing versus outdoor access systems. It includes a control diet without additives. Indoor housing provides limited space per pig while outdoor access provides more indoor and outdoor space per pig. Researchers meticulously measured average daily gain, average daily feed intake, feed conversion ratio, ultrasonic carcass composition, blood hematocrit levels, and the occurrence of observed illnesses. These measurements show how each treatment affected pig health and performance.

3

What is the difference between indoor and outdoor access housing and why is it important?

Outdoor access systems offer pigs more space with bedded concrete indoors and access to an outdoor area. The indoor system provides less space per pig. The OUT system provides more space, which can reduce stress and improve the overall welfare of the pigs. This is important for promoting pig health and growth. The inclusion of outdoor access systems is a key element of the study as it focuses on the environmental impact on pig well-being.

4

What is the significance of tetracycline in the study?

Tetracycline is a subtherapeutic antibiotic used in the study. The research is particularly relevant because legislative bans on antibiotic use in livestock are gaining traction globally. The study's goal is to identify alternatives to antibiotics that not only maintain but also improve pig performance and health. The research is addressing concerns about antibiotic resistance in livestock, promoting both animal welfare and sustainable practices.

5

What are the broader implications of the study's findings for the swine industry?

The study investigated how Bio-Mos and outdoor access could improve pig health and growth, which is important for the swine industry. The study used a 3 x 2 factorial experiment involving 360 pigs. The experimental design allowed researchers to assess the impacts of Bio-Mos and outdoor housing. The key indicators include average daily gain, feed intake, feed conversion ratio, and carcass composition. By integrating these natural feed additives and optimizing housing conditions, the industry can move towards more sustainable and responsible practices to improve overall production efficiency.

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