Surreal digital illustration of a man, veins branching outwards, representing health and improved blood flow after treatment.

Unexpected Side Effect? How Vein Treatment Could Be Changing More Than Just Your Legs

"A recent study reveals an unusual consequence of endovenous ablation, prompting a deeper look at its effects on male health and wellness."


For years, people have sought treatments for varicose veins, those unsightly and often uncomfortable bulges that can appear on the legs. Endovenous ablation, a minimally invasive procedure, has become a popular solution. But a recent study has unearthed a surprising side effect: an increase in penile tumescence (swelling) after the procedure. This revelation opens a new conversation about the scope of these treatments and their potential effects beyond the targeted veins.

This unexpected finding, published in the Journal of Vascular Surgery: Venous and Lymphatic Disorders, prompts a deeper exploration of how these treatments affect the body. The study's authors investigated the impact of endovenous ablation of the great saphenous vein (GSV) on erectile function, and the results have far-reaching implications. This article delves into the study's findings, offering a comprehensive look at the research and its implications.

This isn't just a medical curiosity. It's a reminder of how interconnected our bodies are and how treatments targeting one area can have unforeseen consequences elsewhere. As we explore the study's data, we will also consider the broader context of men's health and the importance of informed consent when considering any medical procedure.

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Practice Trends and Patient Impact

Endovenous ablation is used by a wide variety of medical subspecialists to manage chronic venous disease, with differing levels of formal training. A United States analysis found that the number of ablations per patient was higher among specialties without formal vascular training. The researchers said these data could help establish better guidelines and governance, while cautioning that averages do not apply equally to every patient and that some patients require more than two ablations.

From Stripping to Endovenous Techniques

High ligation and stripping has been replaced in many countries by endovenous techniques, although multiple techniques remain available. Endovenous thermal ablation, primarily endovenous laser ablation and radiofrequency ablation, works by occluding the incompetent vein from within. This approach avoids the traditional stripping procedure, but the available methods differ, and treatment selection and outcomes can vary by clinical situation.

The Rise of Thermal Ablation

Endovenous thermal ablative procedures were introduced in 2001, marking a major shift in the treatment of varicose veins. A 2014 account describes two Dutch dermatologists pioneering endovenous laser ablation and adopting these minimally invasive techniques in surgical practice. Endovenous thermal ablation using radiofrequency or laser subsequently replaced traditional high ligation and stripping in recommendations from leading vascular societies in the United States and United Kingdom.

What the Study Revealed: Unpacking the Link Between Vein Treatment and Penile Tumescence

Surreal digital illustration of a man, veins branching outwards, representing health and improved blood flow after treatment.

The study, which focused on patients undergoing endovenous ablation for GSV issues, used questionnaires to assess erectile function. The researchers were particularly interested in the degree of glans penis tumescence (swelling) during erections. While the primary aim was to evaluate the impact on erectile function, the results took an interesting turn.

The study found that approximately 11% of the participants reported an increased glans tumescence after the procedure. This was a notable contrast to their pre-operative state. While the effect wasn't linked to an overall improvement in erectile function, it was a clear indication that something was happening.

  • The study included 62 patients.
  • Seven patients (11%) reported increased glans tumescence after surgery.
  • The effect was observed at both one week and three months post-operation.
  • No significant improvement in overall erectile function was observed.
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New Comparisons of Minimally Invasive Options

Recent research continues to compare endovenous laser ablation and radiofrequency ablation with conventional surgery and with one another. These minimally invasive therapies have been described as preferred alternatives because they offer shorter recovery times and improved patient satisfaction. A 2025 study also examined short-term outcomes of one-stop versus two-staged endovenous laser ablation for varicose veins and iliac vein disease.

Complications and Long-Term Failure

Although endovenous ablation has largely replaced ligation and stripping for great saphenous vein treatment, its complications require attention. A review of randomized controlled trials noted that studies often emphasized efficacy while giving less attention to short-term complications. Separate five-year follow-up research compared the complications and failures associated with endovenous laser ablation and radiofrequency ablation, showing why long-term evaluation remains important.

Choosing Among Treatment Options

Comparisons among vein-treatment approaches generally weigh invasiveness, recovery, patient experience, durability, and the possibility of complications or treatment failure. Endovenous methods may offer practical advantages over traditional surgery, but the best option can depend on the vein pattern, technique, and patient characteristics. Because outcomes are not identical across procedures, treatment decisions are best individualized with appropriate clinical assessment.

The implications of this finding are twofold. First, it highlights the importance of considering the full range of effects when undergoing medical treatments. Second, it underscores the interconnected nature of the human body, where addressing one issue can inadvertently affect another.

Informed Choices: Navigating Your Health with Confidence

This study serves as a reminder of the importance of open communication between patients and healthcare providers. As endovenous ablation and similar procedures become more common, understanding the full scope of potential effects—both intended and unintended—is crucial. Patients should be fully informed about all potential outcomes, empowering them to make informed decisions about their health and well-being.

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A More Nuanced View of Ablation

The available material presents endovenous ablation as an established but varied group of treatments rather than a single uniform procedure. Its benefits must be considered alongside differences in technique, operator training, complications, and the potential need for additional treatment. A balanced interpretation therefore requires attention to both short-term recovery and longer-term effectiveness.

Growth and Technological Development

Market reports project continued growth for endovenous ablation devices from 2025 onward. The cited drivers include the rising prevalence of venous diseases, greater awareness of minimally invasive options, technological advancements, expanding regional markets, and evolving clinical practices. One forecast covers the 2026-2035 period, suggesting that innovation and broader adoption will remain central themes.

Long-Term Outcomes and Patient Selection

Long-term evaluation extends beyond whether a vein is successfully treated and includes venous hemodynamics, safety, and outcomes in patients with additional risk factors. A 10-year study of endovenous laser ablation using a 1470 nm diode laser examined both long-term effectiveness and changes in lower-extremity venous hemodynamics. Other research has focused on patients with a history of deep vein thrombosis, for whom clinicians have particular concern about postprocedural venous thromboembolism.

Experience Beyond the Procedure

For patients, the real-world impact of vein treatment may include recovery demands, satisfaction with results, and the possibility of needing further care. These experiences can differ according to the technique used, the clinician's training, and the patient's underlying venous condition. Individual consultation remains important because average outcomes do not necessarily describe every patient's treatment journey.

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1016/j.jvsv.2018.06.014, Alternate LINK

Title: Transient Increased Tumescence Of The Glans Penis During Penile Erection After Endovenous Ablation Of The Great Saphenous Vein

Subject: Cardiology and Cardiovascular Medicine

Journal: Journal of Vascular Surgery: Venous and Lymphatic Disorders

Publisher: Elsevier BV

Authors: Jens Cordes, Michael Zimbelmann, Axel S. Merseburger, Mario Kramer, Reinhard Vonthein, Hartwig Büttner, Andreas Recke, Birgit K. Kahle

Published: 2019-05-01

Everything You Need To Know

1

What is endovenous ablation and why is it used?

Endovenous ablation is a minimally invasive procedure commonly used to treat varicose veins, which are often unsightly and uncomfortable bulges that appear on the legs. It aims to address issues with the great saphenous vein (GSV). While effective for its intended purpose, a recent study revealed a surprising side effect related to male sexual function.

2

What unexpected side effect was discovered in a recent study about endovenous ablation?

A recent study published in the *Journal of Vascular Surgery: Venous and Lymphatic Disorders* found that some men who underwent endovenous ablation experienced an increase in glans penis tumescence (swelling) after the procedure. Specifically, the study focused on endovenous ablation of the great saphenous vein (GSV) and its effects on erectile function, noting this unexpected change in approximately 11% of participants.

3

Does the increased penile tumescence observed after endovenous ablation translate to improved erectile function?

The study indicated that while approximately 11% of participants experienced increased glans tumescence after undergoing endovenous ablation for GSV issues, this effect did not correlate with an overall improvement in erectile function. The study included 62 patients, and the effect was observed at both one week and three months post-operation.

4

Why is it important to discuss the potential side effects of treatments like endovenous ablation with a healthcare provider?

Discussing potential side effects of endovenous ablation, including the surprising effect on glans tumescence, is crucial because it underscores the interconnected nature of the human body. Addressing an issue such as varicose veins and the great saphenous vein (GSV) can inadvertently affect other areas, such as male sexual function. Open communication ensures patients are fully informed and can make empowered choices about their health.

5

What are the broader implications of the study's findings on endovenous ablation, especially concerning patient care and informed consent?

The study's findings highlight the importance of considering the full range of effects when undergoing medical treatments like endovenous ablation of the great saphenous vein (GSV). The fact that 11% of participants experienced increased glans tumescence, even without an improvement in erectile function, suggests that treatments targeting one area can have unforeseen consequences elsewhere. This reinforces the need for healthcare providers to fully inform patients about all potential outcomes, empowering them to make informed decisions about their health and well-being. It also calls for further research into the mechanisms behind these unexpected effects to better understand and manage them.

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