Brightly colored chemotherapy room with children playing.

Turning Chemotherapy into Playtime: How 'Chemo-tecas' Boost Kids' Wellbeing

"Discover how colorful, play-filled environments are transforming outpatient chemotherapy for children, making treatment less stressful and more effective."


In healthcare, creating welcoming and supportive environments can significantly impact patients, especially children. Traditional healthcare settings can be intimidating, and innovative approaches are needed to make medical experiences less stressful.

The National Humanization Policy emphasizes comprehensive care, highlighting the importance of creating welcoming and ethical environments within healthcare. This includes making hospital or outpatient care experiences less painful and stressful, emphasizing free visiting hours, involving loved ones, improving physical surroundings, and promoting play.

For children undergoing chemotherapy, integrating play can significantly improve their experience. Recognizing this, the Pediatric Oncology Institute in São Paulo developed 'Quimioteca Fundação Orsa', an outpatient clinic designed to combine chemotherapy with play, aiming to reduce discomfort and improve wellbeing. This article explores how this approach transforms the treatment experience from the perspective of the children's caregivers.

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Pediatric Chemotherapy Safety

Pediatric treatment plans can include oral chemotherapy taken daily for days, weeks, or months. The Wiley article notes that mercaptopurine may require periodic dose adjustments as a patient’s physiology changes. Standard 3.10 requires a licensed pharmacist to verify chemotherapy orders before dispensing or administering them in health care settings treating patients younger than 18; adult ambulatory settings may not include a pharmacist.

Sidney Farber and Early Chemotherapy

A Springer chapter traces the advent of cancer chemotherapy to Sidney Farber’s seminal investigations in the 1940s. St. Baldrick’s describes Farber as a pioneering pediatric pathologist who discovered that chemotherapy drugs could treat children with cancer. Its account notes that he worked alone and was often ridiculed, while chemotherapy offered doctors a new weapon against childhood cancer.

The 'Chemo-teca' Effect: How Play Transforms Treatment

Brightly colored chemotherapy room with children playing.

The Quimioteca Fundação Orsa integrates recreational activities into the chemotherapy room. The key findings from the research on the facility suggest that a play-filled environment positively influences treatment quality and children's overall wellbeing. Caregivers noted that the environment helped to:

The research indicates that the caregivers overwhelmingly viewed the 'Chemo-teca' experience as positive, noting specific improvements:

  • Reduced stress and anxiety associated with treatment.
  • Distracted children from pain and discomfort.
  • Made the environment more pleasant and less intimidating.
  • Contributed to a more positive and engaging treatment experience.
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Evidence and Areas for Improvement

A review of hospital play interventions found that most studies were case studies and that scientific evidence was limited for determining play’s precise clinical effectiveness. In a study of a quimioteca in São Paulo, companions of children receiving outpatient chemotherapy reported that its colorful setting, toys, and leisure activities positively influenced perceived treatment quality and child wellbeing. Despite the positive evaluation, they also identified attention and care as areas needing improvement.

Play Interventions and Measured Outcomes

In a randomized controlled study, children in the therapeutic-play group had lower nausea-vomiting severity than controls at 6 hours after chemotherapy (HL median difference −1.00, 95% CI −1.00 to 0.00; p = 0.002), with a larger difference at 24 hours (HL median difference −1.00, 95% CI −1.00 to −1.00; p < 0.001). A separate randomized trial studied stress-ball play during port-a-cath needle insertion and reported an adjusted Wong-Baker FACES pain score 1.66 points lower in the intervention group than in controls. The reported scores were 5.17 versus 6.83, corresponding to moderate versus severe pain, respectively.

The physical environment and the availability of toys was found to directly influence the quality of treatment. Caregivers appreciated having professionals dedicated to engaging children in play, further contributing to a supportive atmosphere. Caregivers suggested even more frequent and diverse play activities, highlighting the ongoing need for improvement and adaptation.

Creating a New Standard for Pediatric Care

The Quimioteca Fundação Orsa provides a compelling model for integrating play and medical treatment. The positive feedback from caregivers underscores the potential of such environments to improve the chemotherapy experience for children.

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Emerging Pediatric Cancer Approaches

The inaugural AACR Pediatric Cancer Progress Report 2025 highlights molecularly targeted therapies, immunotherapies, and genomic profiling that informs surveillance and treatment decisions. Its first-of-its-kind report, published in the journal on February 4, 2026, covers progress against pediatric cancers over the past decade and describes these developments as reshaping diagnosis, surveillance, and treatment. The report presents these approaches as areas of progress, not as a guarantee of outcomes for individual patients.

Play Spaces Alongside Ongoing Care Needs

The article on Chemo-tecas describes them as spaces that blend medical treatment with play and presents them as a way to improve children’s wellbeing and treatment experience. The American Academy of Pediatrics notes that pediatric cancer survivors need access to emerging technologies aimed at reducing or better managing treatment toxicities. It also emphasizes that, with advances in treatment and survival, pediatric oncology patients continue to need longitudinal, multidisciplinary subspecialty care.

Caregiver and Clinician Perspectives

A descriptive quantitative study examined the opinions of adults accompanying children ages 2 to 12 who were undergoing chemotherapy about the Orsa Foundation’s “Chemo-teca.” Separately, a July 2021 cross-sectional study investigated how real-world data and real-world evidence are used in pediatric literature to inform medicine efficacy. A JAMA Network pediatric cancer collection describes a study collecting and analyzing clinician and parent perspectives on clinical-trial participation among children from historically marginalized groups.

By prioritizing a child-friendly atmosphere and offering engaging activities, healthcare providers can significantly reduce the stress and anxiety associated with chemotherapy, contributing to better overall outcomes.

The 'Chemo-teca' concept encourages healthcare facilities to consider creative and humanized approaches to care, fostering a more supportive and healing environment for young patients and their families.

What broader play-intervention reviews counted

  • 15 of 16In a review of play therapy for children with leukemia, 15 of 16 studies reported beneficial effects on psychological or physical problems.[1]

What these results add-and what they do not establish

Taken together, the reviews point to possible benefits across emotional and physical concerns, but they do not give one consistent estimate of how large those benefits are.[1] [2]

The anesthetic-use result concerns medication use, not a direct measure of children’s wellbeing, so it adds a different kind of outcome to the evidence about play and care.[3]

How the Chemo-teca evidence fits wider care approaches

The Chemo-teca findings came from semi-structured interviews with 54 companions during outpatient chemotherapy, so they capture caregivers’ accounts rather than a direct clinical measurement.[4]

Related literature on playful strategies has often focused on work in developed-country settings and on isolated interventions, which leaves the broader range of care settings less represented.[5]

Playful strategies in pediatric cancer care can include gamification, virtual reality, robotics, and the design of healthcare environments; they may also serve psychosocial support and health education.[5]

The clinical encounter itself can contribute to a healing environment through listening and answering questions, explaining procedures, and distraction, alongside the physical setting.[5]

What remains unanswered about play and chemotherapy care

  • Would caregivers’ positive accounts of the Chemo-teca correspond to changes in outcomes measured directly in children, rather than perceptions reported in interviews?[4]
  • How well do findings from isolated playful interventions and settings concentrated in developed countries apply to broader pediatric cancer-care environments?[5]

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

Everything You Need To Know

1

What exactly is a 'Chemo-teca'?

A 'Chemo-teca' is an innovative space designed to blend medical treatment with play, specifically for children undergoing chemotherapy. It's a play-filled environment within an outpatient clinic, like the 'Quimioteca Fundação Orsa' in São Paulo. The goal is to transform the treatment experience, making it less stressful and more enjoyable for children by integrating recreational activities into the chemotherapy room. This approach contrasts with traditional healthcare settings, which can be intimidating.

2

Why are 'Chemo-tecas' considered important?

The 'Chemo-tecas' are important because they significantly improve children's wellbeing and the quality of their chemotherapy treatment. The integration of play helps reduce stress and anxiety, distracts from pain and discomfort, and makes the environment less intimidating. This results in a more positive and engaging treatment experience for children, which is crucial for their overall health and emotional well-being during a difficult time. Caregivers reported overwhelmingly positive experiences.

3

What is the 'Quimioteca Fundação Orsa'?

The 'Quimioteca Fundação Orsa' is a specific example of a 'Chemo-teca'. Located in São Paulo, it's a model for integrating play and medical treatment. It was developed by the Pediatric Oncology Institute. It features a chemotherapy room designed to include recreational activities. The feedback from caregivers has been very positive, which underscores the potential of such environments to improve the chemotherapy experience for children and providing a compelling case study.

4

How does the National Humanization Policy relate to 'Chemo-tecas'?

The National Humanization Policy emphasizes the importance of creating welcoming and ethical environments within healthcare, which is crucial in the context of 'Chemo-tecas'. This policy highlights the need to make healthcare experiences less stressful and more supportive. This includes elements like free visiting hours, involving loved ones, improving physical surroundings, and promoting play, which align with the principles behind 'Chemo-tecas'. This policy underscores the need to address the overall patient experience.

5

What specific benefits did caregivers report from the 'Chemo-teca' experience?

Caregivers reported several specific improvements due to the 'Chemo-teca' environment. These include a reduction in stress and anxiety, distraction from pain and discomfort, a more pleasant and less intimidating atmosphere, and a more positive and engaging treatment experience. They also valued the presence of professionals dedicated to engaging children in play, which further contributed to the supportive atmosphere. Caregivers suggested even more frequent and diverse play activities, indicating the ongoing need for improvement and adaptation of 'Chemo-tecas'.

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