Surreal digital illustration symbolizing combined kV/MV CBCT imaging advancements in medical diagnostics.

Revolutionizing Medical Imaging: Can Combined kV/MV CBCT Scans Reduce Scan Time and Metal Artifacts?

"A deep dive into a new study exploring the potential of combined kilovoltage/megavoltage cone-beam computed tomography (kV/MV CBCT) with a high-DQE MV detector to enhance image quality and streamline medical imaging processes."


In the ever-evolving landscape of medical imaging, precision and efficiency are paramount. State-of-the-art medical linear accelerators are now commonly equipped with two imaging systems: an electronic portal imaging device (EPID) used with the treatment beam and an orthogonal kilovoltage (kV) system. These systems offer complementary information, improving localization accuracy and treatment quality.

Cone-beam computed tomography (CBCT) or kV planar imaging is typically used for patient setup, beam gating, and beam delivery verification, while the MV system is more commonly used for treatment quality assurance and exit dosimetry. Recent research explores the potential of combined kilovoltage/megavoltage (kV/MV) imaging as an avenue for innovation, focusing on reducing scan times and minimizing metal artifacts—common challenges in radiotherapy and diagnostics.

A recent study investigates the use of combined kV/MV CBCT imaging with a high Detective Quantum Efficiency (DQE) MV detector. The goal is to determine if this advanced setup can generate acceptable quality pre-treatment CBCT images at clinically acceptable dose levels. By addressing limitations related to scan time and image distortion, this research opens new possibilities for enhancing image-guided radiotherapy applications.

How Does Combined kV/MV CBCT Imaging Work?

Surreal digital illustration symbolizing combined kV/MV CBCT imaging advancements in medical diagnostics.

The study, conducted using a Truebeam system, combined data from both 6MV and 100kVp projections. The MV data was acquired using a prototype EPID containing two scintillators: a standard copper-gadolinium oxysulfide (Cu-GOS) screen and a prototype focused cadmium tungstate (CWO) pixelated “strip.” The kV data was acquired using a standard onboard imager. Image quality was then evaluated using phantoms—an 18-cm diameter electron density phantom and a 20-cm diameter Catphan phantom—analyzing contrast and resolution.

To simulate metal artifact reduction (MAR), researchers replaced two CIRS phantom inserts with steel rods. They based reconstruction methods on combining MV and kV data into a single sinogram, using mostly kV raw data and replacing rays corrupted by metal with MV data. For scan time reduction (STR), projections from partially overlapping kV and MV acquisitions were combined, and the resultant images were compared against MV-only and kV-only reconstructions.
  • Scan Time Reduction (STR): Projections from partially overlapping 105° kV and MV acquisitions were combined to create a complete data set, potentially achievable in just 18 seconds.
  • Metal Artifact Reduction (MAR): The reconstruction process utilized primarily kV raw data, with MV data selectively replacing rays corrupted by metal, thus reducing distortions.
  • Dose Levels: The total absorbed dose for MAR was approximately 0.7 cGy, while the STR combined acquisition resulted in about 2.5 cGy.
The results indicated that the high-DQE MV detector significantly improved image quality for both STR and MAR applications. In combined kV/CWO STR reconstruction, all contrast inserts were visible, whereas only two were detectable in the kV/Cu-GOS image due to high noise levels. Similarly, in kV-MV MAR reconstructions, streaking artifacts were substantially reduced, making all inserts clearly visible in the kV/CWO image.

The Future of Medical Imaging

This study confirms that a high-DQE MV detector can be effectively applied to generate high-quality combined kV/MV images for SRT and MAR, using clinically acceptable doses. By significantly reducing scan times and minimizing artifacts caused by metal implants, this technology promises to improve diagnostic accuracy and streamline radiotherapy planning. As medical imaging technology continues to advance, innovations like combined kV/MV CBCT imaging will play a crucial role in shaping the future of healthcare.

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