Hands washing with golden hand-rub solution on a map of Africa

Hand Hygiene Heroes: How Local Production Fought Ebola and Can Save Lives Now

"Discover the untold story of how Liberia and Guinea built their own hand-rub solution production during the Ebola crisis, and how this model can bolster public health globally."


The 2014-2016 Ebola outbreak in West Africa was more than just a health crisis; it was a harsh reminder of how fragile healthcare systems can be. One of the biggest problems was the lack of basic infection control measures. This gap caused human-to-human transmission to skyrocket, turning a dire situation into a full-blown humanitarian disaster. But amidst the chaos, a beacon of hope emerged: the local production of hand-rub solution in Liberia and Guinea.

In the summer of 2014, the Geneva University Hospitals (HUG) stepped up. They conducted an IPC assessment and, with support from the Swiss Agency for Development and Cooperation and the Humanitarian Aid Unit (SDC/HA), launched a project tailored to local needs. The goal? To build local capacity for producing alcohol-based hand-rub solution (ABHRS) using the World Health Organization (WHO) formula.

This initiative wasn't just about providing a quick fix. It was about laying the groundwork for sustainable change. By training local pharmacists and equipping hospitals with the necessary tools and knowledge, the project aimed to promote safer care and reduce dependence on foreign aid. It was a bold move, and the results were impressive: over 8,000 bottles of hand-rub solution produced, and a newfound sense of empowerment within the local healthcare systems.

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Ebola's Toll: A Deepening Crisis in Central Africa

Ebola is a highly contagious disease caused by viruses mostly associated with fruit bats, often resulting in viral haemorrhagic fever, and more than 40 outbreaks have been documented since its first emergence in 1976. The current outbreak marks the 17th in the Democratic Republic of the Congo and has become the deadliest in the country's history, with deaths surpassing the 2,299 recorded in the 2018-2020 outbreak. The crisis has also spread across borders, with Uganda declaring its own outbreak of Ebola disease caused by Sudan ebolavirus. The 2026 Ebola outbreak in Africa has sent shockwaves across the global health community, marking one of the most alarming viral crises on the continent in recent years.

Containment Under Fire: Why Standard Ebola Response Keeps Falling Short

Standard Ebola response has historically relied on supportive care for the ill and isolating them to limit the spread of the virus, as there has been no cure or vaccine. The 2014 West Africa epidemic, the largest and deadliest in history, was traced back to a 2-year-old boy in Meliandou, Guinea, who reportedly came in contact with an infected fruit bat. However, the current outbreak in eastern DRC is unfolding in a region already facing acute humanitarian needs, where armed conflict and mass displacement have significantly constrained humanitarian access and complicated the delivery of life-saving assistance. In a controversial shift, the Trump administration has begun flying U.S. citizens exposed to the virus to Europe and Kenya for treatment, departing from past practice of sending them to state-of-the-art domestic facilities.

Five Decades of Ebola: From First Discovery to Repeated Outbreaks

Ebola first emerged in 1976 and has since caused close to 40 outbreaks across Africa. The virus is a rare but deadly pathogen that causes severe illness, organ damage, and sometimes internal bleeding. The CDC maintains a comprehensive record of all known cases and outbreaks of Ebola disease, including the current outbreak affecting the DRC and Uganda. Past outbreaks, such as those in Guinea, Sierra Leone, and Liberia, have demonstrated the devastating capacity of the virus to tear through communities with limited health infrastructure.

From Crisis to Capacity: Building a Local Solution

Hands washing with golden hand-rub solution on a map of Africa

The project kicked off during the peak of the Ebola outbreak in Liberia (Fall 2014) and continued through the recovery period in Guinea (September 2015). Twenty-one pharmacists in Liberia and 22 in Guinea were selected for intensive training. Each participant received a year's worth of laboratory equipment, chemical products, personal-use containers, and bioethanol. This wasn't just a handout; it was an investment in local expertise.

Selecting the right production sites was crucial. The Ministries of Health (MoH) prioritized hospitals with maternity departments, ensuring safer care for mothers and children. They also aimed for a balance between urban and rural facilities, ensuring that the benefits reached all corners of the countries. Each site had to provide a dedicated, secure space with windows for aeration and a sink with running water – basic but essential requirements.

The training itself was a blend of theory and hands-on practice, led by international experts. The curriculum was carefully adapted from previous experiences in sub-Saharan Africa. Here’s what the training covered:
  • Validation of the WHO formula by the MoH
  • Registration of the hand-rub solution as a pharmaceutical product
  • Practical sessions on ABHRS production
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Surging Case Counts and Delayed Detection

Research indicates that the Ebola outbreak in the DR Congo began earlier than initially declared, with authorities reporting more than 3,530 cases and 1,556 deaths since it was officially recognized in mid-May. The outbreak has now become the world's second-largest by recorded infections, highlighting a critical gap in early detection. According to researchers, outbreak response often begins only after infections are confirmed, while long-term prevention in high-risk communities remains inconsistent. Uganda's experience with a major Sudan Ebola outbreak in 2022 further underscores the recurring nature of these threats in the region.

Systemic Failures Hampering the Ebola Response

A WHO independent panel has called out significant flaws in the Ebola response, noting that while improved methods are being incorporated as they are developed, it will take many more months of continued hard work to end the outbreak. The failure to fight Ebola epidemics in a timely manner is not new; poorly coordinated outbreak responses represent a well-known systems failure that will likely arise with every future epidemic. Doctors Without Borders previously declared Ebola was 'out of control,' emphasizing that with no cure or vaccine, containment depends entirely on supportive care and isolation — tools that are difficult to deploy in conflict-affected regions.

Comparing Outbreaks: 2018 vs. 2026

The DRC's latest Ebola outbreak has claimed more than 200 lives, with cases concentrated in North Kivu and Ituri provinces, prompting direct comparisons with the devastating 2018-2020 outbreak. As the outbreak widens, the U.S. response has been described as 'opaque, confusing and contradictory,' with 359 confirmed cases including one American and 61 deaths reported at one point during the crisis. The Ebola outbreak has appeared in many countries across Africa and continues to spread, raising the stakes for a coordinated regional and international response.

Despite the project's success, the road wasn't always smooth. One major challenge was the scarcity of bioethanol in Liberia and Guinea. Since local trade had been disrupted by the epidemic, all necessary materials had to be sourced through the project. Bioethanol, based on WHO recommendations to produce ABHRS, was imported. Looking ahead, the long-term sustainability of ABHRS production hinges on the local government's commitment, creating demand, purchasing materials, and the continuous support of local partners.

A Lasting Legacy

The Ebola outbreak underscored the vital role of hand hygiene in preventing disease transmission. By building local capacity in ABHRS production, Liberia and Guinea not only addressed an immediate crisis but also laid the foundation for stronger, more resilient healthcare systems. The lessons learned from this experience can be applied worldwide, empowering communities to take control of their health and protect themselves from future outbreaks. The project demonstrated that it was feasible to build local capacity in ABHRS production during an emergency and in limited-resource settings when materials and training are provided. Future programs in similar contexts should identify and address the factors of sustainability during the implementation phase and provide regular, long-term technical support.

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Experts Warn: The Outbreak Is Far From Over

A WHO expert has warned that the Ebola outbreak will continue for at least six more months, painting a sobering picture of the road ahead. The response has been further complicated by the simultaneous occurrence of a malaria outbreak, with children reportedly sharing rooms with Ebola patients who were not suspected or diagnosed, and no medical records taken. Experts note that Ebola infections in dense populations or urban areas can transmit quickly and become difficult to manage, raising urgent questions about whether available vaccines can help contain the current crisis.

Mapping, Vaccines, and the Limits of Global Health Systems

Emerging research is focused on mapping Ebola in wild animals as a strategy for better disease control, recognizing that the 2014 West Africa outbreak was unprecedented in scale and the first to spread to urban areas. A new Ebola vaccine has shown 100 percent effectiveness in early tests, offering hope amid a crisis that killed over 11,000 people in less than two years during the West Africa epidemic. However, the fundamental lesson remains stark: international health systems are far too weak for an increasingly interconnected, urbanized world, and the failures of public-health infrastructure in one country quickly become the problems of hospitals everywhere.

Preparedness Gaps Across Borders

During the West Africa Ebola epidemic, an infected traveler from Guinea brought the virus into Mali, but immediate identification and monitoring of all contacts successfully prevented a broader outbreak. Health system preparedness for Ebola remains a critical concern across vulnerable regions, with researchers examining the impacts of the West Africa outbreak and drawing lessons from COVID-19 for government and public health preparedness. Notably, the Zaire strain of Ebola behind the current outbreak is the same one responsible for most previous outbreaks, yet controlling it continues to prove extraordinarily difficult due to systemic weaknesses in affected health systems.

From West Africa to Dallas: How Ebola Tests Every System It Touches

Mathematical modeling of the epidemiological distribution and transmission patterns of Ebola during the African outbreak has been critical for understanding how the virus spreads and for planning vaccination strategies. Canada's preparedness for Ebola has been cited as having 'led the world,' with health experts expressing confidence that even if a case emerged domestically, the country was well equipped to handle it. Research modeling the international spread of the outbreak — beginning with the first case outside Africa in Dallas — estimates the probability of Ebola appearing in countries around the world, underscoring that no nation is truly insulated from the consequences of weak global health infrastructure.

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1017/s1049023x18000985, Alternate LINK

Title: Building Local Capacity In Hand-Rub Solution Production During The 2014-2016 Ebola Outbreak Disaster: The Case Of Liberia And Guinea

Subject: Emergency Nursing

Journal: Prehospital and Disaster Medicine

Publisher: Cambridge University Press (CUP)

Authors: Frederique A Jacquerioz Bausch, Olivia Heller, Loséni Bengaly, Béatrice Matthey-Khouity, Pascal Bonnabry, Yakaria Touré, Garrison J Kervillain, Elhadj Ibrahima Bah, François Chappuis, Olivier Hagon

Published: 2018-11-05

Everything You Need To Know

1

Why was local production of hand-rub solution important during the Ebola outbreak in Liberia and Guinea?

During the Ebola outbreak in Liberia and Guinea, the local production of alcohol-based hand-rub solution (ABHRS) became a critical component of infection control. The project, initiated by Geneva University Hospitals (HUG) with support from the Swiss Agency for Development and Cooperation and the Humanitarian Aid Unit (SDC/HA), focused on training local pharmacists to produce ABHRS using the World Health Organization (WHO) formula. This ensured that healthcare workers and the public had access to a vital tool for preventing the spread of the disease.

2

What were the main obstacles in producing alcohol-based hand-rub solution locally, and how can these be overcome for future sustainability?

The key challenges faced during the local production of alcohol-based hand-rub solution (ABHRS) included the scarcity of bioethanol, a crucial ingredient for ABHRS production. Because the Ebola epidemic disrupted local trade, bioethanol had to be imported. To ensure long-term sustainability, it's vital that local governments commit to purchasing materials, creating demand, and maintaining support from local partners. This also involves validating the World Health Organization (WHO) formula by the Ministries of Health (MoH) and registering the hand-rub solution as a pharmaceutical product.

3

What did the training program for local pharmacists in Liberia and Guinea involve, and how did it ensure effective production of alcohol-based hand-rub solution?

The training program involved selecting pharmacists in Liberia and Guinea for intensive training, where each participant received laboratory equipment, chemical products, personal-use containers, and bioethanol for a year. The training curriculum, adapted from experiences in sub-Saharan Africa, included validation of the World Health Organization (WHO) formula by the Ministries of Health (MoH), registration of the alcohol-based hand-rub solution (ABHRS) as a pharmaceutical product, and practical sessions on ABHRS production. This hands-on approach ensured that local healthcare professionals were well-equipped to produce and utilize ABHRS effectively.

4

How were the locations for hand-rub production sites selected, and what impact did this have on the affected communities?

The Ministries of Health (MoH) prioritized hospitals with maternity departments and aimed for a balance between urban and rural facilities when selecting production sites. Each site needed a dedicated, secure space with windows for aeration and a sink with running water. By focusing on these essential facilities, the program ensured safer care for mothers and children and distributed the benefits of local alcohol-based hand-rub solution (ABHRS) production across different areas, helping to combat the spread of Ebola and reinforce infection control practices where they were most needed.

5

What are the broader lessons and implications of the hand-rub production project in Liberia and Guinea for global public health and future outbreaks?

The success of local alcohol-based hand-rub solution (ABHRS) production in Liberia and Guinea has broad implications for global public health. By demonstrating that it is feasible to build local capacity during emergencies, even in limited-resource settings, the project has set a precedent for empowering communities to take control of their health. Future programs should focus on identifying and addressing factors of sustainability during implementation, and provide regular, long-term technical support to ensure the continued availability of ABHRS and the strengthening of healthcare systems.

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