Surreal illustration of a key made of opioid pills unlocking a clinic door, symbolizing improved opioid management.

Cracking the Code: How Clinics Can Improve Opioid Management

"A Resident Clinic's Journey to Better Quality of Care and Resource Efficiency."


Chronic pain management and responsible opioid prescribing are critical issues in primary care, particularly within teaching environments. Resident clinics often face unique hurdles due to trainee schedules, varying levels of experience, and the need for consistent education on best practices. Ensuring patient safety and quality care in these settings requires innovative solutions.

The opioid epidemic continues to be a major public health concern, with significant economic and social costs. Guidelines from organizations like the CDC emphasize the importance of careful opioid prescribing practices, including risk assessment, toxicology screening, and patient agreements. Primary care providers play a vital role in managing chronic pain and preventing opioid misuse, making it essential to equip them with the necessary tools and support.

This article explores how one internal medicine residency clinic addressed these challenges through a quality improvement project. By implementing strategies focused on standardization, team-based care, and the utilization of mid-level providers, the clinic aimed to improve adherence to quality metrics, optimize resource utilization, and ultimately enhance the care provided to patients on chronic opioid therapy.

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Chronic Pain and Its Impact

The CDC’s November 2024 data brief describes chronic pain and high-impact chronic pain—pain that often restricts life or work activities—as common reasons adults seek medical care. The brief associates both with decreased quality of life, opioid misuse, increased anxiety and depression, and unmet mental health needs. It also reports that 20.4% of U.S. adults had chronic pain in 2019. (Reference URL 1; Reference URL 2)

Guideline-Based Opioid Prescribing

CDC guidance prefers nonpharmacologic and nonopioid pharmacologic therapies for chronic pain. Clinicians should consider opioid therapy only when anticipated benefits for both pain and function outweigh the risks, and combine opioids with nonpharmacologic and nonopioid therapies when appropriate. The CDC guideline also recommends urine drug testing before opioid therapy begins and consideration of at least annual testing during treatment. (Reference URL 1; Reference URL 2)

How Opioids Became Central to Pain Care

A 2018 review describes 20th-century pain management as becoming predominantly pharmacologic. Perceptions that pain was undertreated contributed to increased opioid use, first for cancer-related pain and later for noncancer pain, without the multidimensional care originally intended. Another review says the presumption that opioids were safe and effective for chronic pain contributed to overreliance and a significant reduction in multidisciplinary pain centers across the United States. (Reference URL 1; Reference URL 2)

Standardizing Care: The Power of EHR Templates and Workflow Redesign

Surreal illustration of a key made of opioid pills unlocking a clinic door, symbolizing improved opioid management.

The first phase of the clinic's quality improvement initiative focused on standardizing documentation and streamlining the opioid prescription renewal process. They introduced electronic health record (EHR) templates designed to capture essential information related to chronic pain management, including pain assessment, treatment history, functional status, opioid risk tool results, toxicology screening, opioid agreements, and treatment goals.

A key component of this phase was empowering the registered nurse (RN) to manage opioid prescription renewals. The RN served as the point of contact for patients requesting renewals, reviewed EHR templates for completeness, checked state prescription monitoring program (PMP) data, and ensured that patients had scheduled appropriate follow-up appointments. This system reduced the burden on resident physicians and provided a consistent point of contact for patients.

  • Increased annual toxicology screening from 53% to 81% (P<0.0015).
  • Increased the use of opioid risk assessment tools from 0% to 75.9% (P<0.0001).
  • Increased annual opioid agreements from 13.8% to 53.5% (P<0.0001).
  • Decreased average daily morphine milligram equivalents (MME) from 96.6 mg to 67.6 mg (P = 0.0008).
  • Decreased the average number of annual office visits from 11.1 to 8.9 (P=0.0004).
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What Recent Reviews Report

A systematic review of cyclical medication-management interventions found that they used an average of 2.4 components. Common components included practice standardization (23 studies), clinician feedback (20), and clinician education (18). A separate scoping review of electronic health records in primary care reported favorable findings in half of the studies, including reduced morphine dosage in one study. (Reference URL 1; Reference URL 2)

These changes demonstrate the effectiveness of standardization and workflow redesign in improving adherence to quality measures and optimizing resource utilization. By providing residents with clear guidelines and support, and by empowering nursing staff to take on a greater role in managing opioid prescriptions, the clinic was able to significantly improve the quality of care provided to patients on chronic opioid therapy.

Sustaining Improvements: The Role of Previsit Planning and Huddles

In the second phase of the project, the clinic implemented previsit planning and daily huddles to further enhance quality of care. Before each patient visit, the RN reviewed patient charts to identify any missing quality measures or outstanding issues. During daily huddles, the RN provided verbal reminders to resident physicians to address these issues, review pain-related specialty follow-up, and make any necessary prescription adjustments.

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Toward Personalized, Multidisciplinary Pain Care

An October 2025 article on four decades of progress in chronic pain management identifies precision medicine, technology integration, and safety-centered innovation as future directions. It also highlights continuing challenges that include opioid misuse, variation among patients, and equitable access. A separate 2026 guide describes personalized, multimodal plans based on the biopsychosocial model, new FDA-approved non-opioid medications, and interprofessional care teams as increasingly accessible approaches. (Reference URL 1; Reference URL 2)

While this intervention did not result in significant incremental increases in adherence to quality measures (likely because adherence was already high after the first phase), it did contribute to improved clinic visit utilization and served as a valuable tool for reinforcing policies and sustaining the gains achieved in the first phase. The huddles provided a platform for continuous education and ensured that residents remained focused on providing high-quality care.

This study highlights the importance of a multi-faceted approach to improving opioid management in resident clinics. By combining EHR templates, workflow redesign, and team-based care, clinics can create a sustainable system of care that promotes patient safety, optimizes resource utilization, and provides valuable training opportunities for future physicians. The role of the RN as a point of contact for patients and a moderator for quality control is particularly crucial in these settings.

Two workflow changes in an internal medicine resident clinic

PopulationInternal Medicine resident clinic[1]
SettingSuburban, university-affiliated Internal Medicine resident clinic[1]
Duration2015-2017 academic years[1]
Main outcomeAdherence to quality metrics and office visit utilization[1]
Effect sizeAnnual toxicology increased from 53% to 81%; annual opioid agreement from 13.8% to 53.5%; risk assessment from 0% to 75.9%; average daily MME decreased from 96.6 to 67.7; annual office visits decreased from 11.1 to 8.9.[1]
Times cited6[1]
  • 28.9 MMEAverage daily MME fell by 28.9 MME, from 96.6 to 67.7 MME; the study reports this change as statistically significant (P < 0.0001).[1]Caveat: P < 0.0001
  • 2.2 visitsAnnual office visits fell by 2.2 visits, from 11.1 to 8.9; the study reports this change as statistically significant (P = 0.0004).[1]Caveat: P = 0.0004

How the clinic result appears in later reviews

The same review identified four EHR intervention types: alerts, order sets or preference lists, documentation templates, and care-team communication tools. These are categories in the review, not evidence that each was used in this clinic.[2]

That systematic review also found most included interventions were studied in hospitals and many used a Plan-Do-Study-Act framework. Those review-level observations describe the wider literature, not the setting or design of every included study.[3]

What the two-cycle project can tell us

The project paired changes to clinic documentation and renewal routing with later previsit planning and team huddles, so its results describe a combined quality-improvement effort rather than an isolated tool.[1]

Where the second cycle adds less evidence

  • The later previsit and huddle phase did not add measurable gains in quality-metric adherence, although adherence remained high.[1]

What a follow-up could clarify

  • Would the workflow changes produce similar results in resident clinics with different settings or staffing arrangements?[1]
  • How did the clinic maintain its quality-metric adherence after the study period ended?[1]

Terms used in the study

Plan-Do-Study-Act cycle
The named framework used to structure the before-after quality-improvement intervention.[1]

About this Article -

Written with AI assistance from published research, and reviewed by the Mystum team. See our About page for more information.

This article is based on research published under:

DOI-LINK: 10.1093/pm/pny239, Alternate LINK

Title: Improving Opioid Management And Resource Utilization In An Internal Medicine Residency Clinic: A Before-After Study Over Two Plan-Do-Study-Act Cycles

Subject: Anesthesiology and Pain Medicine

Journal: Pain Medicine

Publisher: Oxford University Press (OUP)

Authors: Rachel Wong, William Carroll, Astha Muttreja, Victor Garcia, Erin Taub, Alice Fernan

Published: 2018-11-23

Everything You Need To Know

1

What was the primary goal of the quality improvement project?

The internal medicine residency clinic addressed challenges of chronic pain and opioid management through a quality improvement project. This involved strategies focusing on standardization, team-based care, and the utilization of mid-level providers. These efforts aimed to improve adherence to quality metrics, optimize resource utilization, and enhance the care provided to patients on chronic opioid therapy.

2

How did the clinic use Electronic Health Record (EHR) templates?

Electronic Health Record (EHR) templates played a crucial role in the clinic's standardization efforts. These templates were designed to capture essential information related to chronic pain management. This included pain assessment results, treatment history, functional status, opioid risk tool results, toxicology screening results, opioid agreements, and treatment goals. By standardizing documentation with EHR templates, the clinic ensured consistency and completeness in patient care.

3

What role did the Registered Nurse (RN) play in the opioid prescription renewal process?

The registered nurse (RN) was empowered to manage opioid prescription renewals. The RN became the primary point of contact for patients needing renewals. They reviewed the EHR templates, checked state Prescription Monitoring Program (PMP) data, and ensured patients had appropriate follow-up appointments. This system alleviated the burden on resident physicians and created a reliable point of contact for patients, improving the efficiency of the renewal process.

4

How did previsit planning and huddles contribute to better patient care?

Previsit planning and daily huddles were implemented to enhance the quality of care further. The registered nurse (RN) reviewed patient charts before visits to identify missing quality measures or outstanding issues. During daily huddles, the RN reminded resident physicians about these issues, reviewed pain-related specialty follow-up, and assisted with any necessary prescription adjustments. These practices ensured that all aspects of patient care were addressed, reinforcing team-based care.

5

What were the key improvements achieved through this quality improvement project?

The clinic's quality improvement project led to several positive outcomes. The percentage of annual toxicology screenings increased from 53% to 81%. The use of opioid risk assessment tools jumped from 0% to 75.9%. Annual opioid agreements increased from 13.8% to 53.5%. The average daily morphine milligram equivalents (MME) decreased from 96.6 mg to 67.6 mg. Finally, the average number of annual office visits went down from 11.1 to 8.9. These improvements demonstrate the effectiveness of the implemented strategies.

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